Methylation, B12, Glutathione, etc.

Some patients have symptoms consistent with a deficiency of methyl donors such as SAMe/AdoMet, either localized to brain regions or elsewhere. Other patients report strange reactions with B vitamins, especially B12 or folate, but without any obvious explanation. This is the place to discuss B vitamins, methyl donors, glutathione, etc.
S
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Why are B12 supplements making my symptoms so much worse?
3 4 5
Replies
88
Views
12K
BlackoutXL
B
Mr. Cat
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Glutathione causing anxiety/irritability
3 4 5
Replies
82
Views
22K
Tammy
Tammy
Pyrrhus
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  • Poll
B12: a simple 5-second poll for everyone
2 3 4
Replies
76
Views
17K
ironlion37
ironlion37
Hip
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CAUTION: Vitamin B12 Sublinguals — The Citric Acid Additive Can Erode Tooth Enamel
6 7 8
Replies
146
Views
98K
L'engle
L'engle
nerd
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What is your understanding of the methylation cycle trap or blockage?
2 3 4
Replies
61
Views
15K
daniariete75
D
C
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The plausibility of NAC inducing b12 deficiency or 'methyl-trap'
2 3
Replies
49
Views
17K
GreenMachineX
G
Pyrrhus
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Low glutathione in ME/CFS brain: a pilot magnetic resonance spectroscopy study at 7 Tesla (Godlewska et al., 2021)
Replies
16
Views
6K
lenora
L
ahmo
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Favorite Choline?
2
Replies
28
Views
15K
Pyrrhus
Pyrrhus
Gondwanaland
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Supplementation with high concentrations of synthetic B6 (pyridoxine) leads to decreased natural vitamin B6 (pyridoxal) function
2
Replies
23
Views
9K
Gondwanaland
Gondwanaland
R
  • Locked
  • Sticky
Documents by Rich Van Konynenburg: Parts 1-7
Replies
7
Views
57K
richvank
R
Cort
Edta
Replies
15
Views
5K
Bexy89
B
Hip
Very noticeable improvements in brain fog using Dr Greg Russell-Jones's transdermal B12 oils (which provide a similar dose to B12 injections)
11 12 13
Replies
257
Views
51K
Jadzhia
J
Y
I feel very bad
2 3 4
Replies
67
Views
3K
linusbert
linusbert
Cort
B-12 - The Hidden Story
185 186 187
Replies
4K
Views
1M
Tiffyshea
T
Y
Iodine protocol, any experiences?
Replies
9
Views
555
datadragon
D
D
Badly needing help with vitamin B2 and b3
Replies
4
Views
518
yellowspain
Y
garyfritz
Transdermal B12 oils
37 38 39
Replies
770
Views
169K
yellowspain
Y
SpinachHands
Choline supplement causing daily PEM even after stopping?
Replies
8
Views
400
almost
almost
B
Feeling ill for months after B12 injection
Replies
13
Views
600
linusbert
linusbert
boohealth
Views on B12--Greg (B12 oils) view vs Rich Van's view--Thoughts?
24 25 26
Replies
511
Views
83K
yellowspain
Y
SpinachHands
Is there a simple guide to methyl and/or choline?
Replies
11
Views
497
Violeta
Violeta
F
Amphetamine type feelings from B vitamins followed by crash
Replies
7
Views
324
Dysfunkion
Dysfunkion
caledonia
Roadblocks to Successful Methylation Treatment
2 3 4
Replies
71
Views
15K
yellowspain
Y
S
Post your current ME/CFS supplement stack and what you're thinking about next.
2
Replies
36
Views
3K
L'engle
L'engle
S
Self administer IV-hydration (and/or methyl-b12 IM) at home
Replies
9
Views
375
kushami
K
M
Looking for an Affordable Source for Injectable B12
Replies
13
Views
750
Keshav
K
Y
How to fight refeeding syndrome?
2
Replies
30
Views
1K
drmullin30
drmullin30
C
Adverse effects from potassium
Replies
18
Views
681
croma
C
B
Problems with hormones/methyl folate/ heavy metals/general methylation
Replies
13
Views
8K
yellowspain
Y
Y
Doubts about B12/b9
2
Replies
34
Views
1K
yellowspain
Y
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