This is what Greg Russell-Jones' B12/B2 protocol yielded me in the six months from Jan 1 till June 30:
(Slight update at the end.)
(You don’t realise how much things have changed till you sit down & do a list.)
Mind:
OCD (songlines going round my head): constant before, now zero
Anxiety: 20% less
General mood: 20% higher
Anhedonia (was occasional): Gone
Mental processing, memory: Not changed (yet?)
Autism: Social skills tons better. Am highly social, no longer introverted.
(I’m a mid-range adult autistic)
Eyes:
Itchy eyes: gone (after several years)
Blurry eyes: no change
Morning eye crust: gone
Energy/CFS:
Physical energy: 3-4 years of chronic fatigue is gone
Exercise tolerance is fine now—no PEM
Muscle weakness: Gone
Somatic sense of anemia (part of CFS): Now gone.
Sleep: Still 9.5h (but down from 12h six months ago)
Food reactions:
Reactivity to oxalate & salicylate: 70% less
Reactivity to histamine: 20% less
(I can eat almost anything I like now, other than too many ferments. No more neurotic diets.)
Miscellaneous:
Orthostatic Intolerance: Gone
Kidneys: No longer ache (The aching was during my Month 4 crash, & felt like a huge detox)
Tongue: No longer furry! Pinkest it’s been in years
Psoriasis: No better
Fine bodywide tremor: This seemed to be a ‘symptom’ of building the B12 levels. Lasted ~2m. Now gone.
Strained hypothyroid voice: now gone
Heart arrythmias: Still have plenty—if anything more than before. (Was a bit paranoid that this is COVID vaccines. Tho on reflection it is likely my potassium getting tanked with rising methylation. Coconut water fixes it instantly.)
Peeing all night: Unchanged
Slow urine stream: Unchanged
Facial colour: huge change: from pasty to pink
Weight has gone from 63 to 66 kg in 6m (very pleasing as I have always been way too skinny)
Hunger has reduced somewhat (which means the propensity to weight gain isn’t a prob)
Insomnia: Unchanged—still quite a lot
Blocked nose at night: 75% less
Tinnitus (mostly from salicylates perhaps): ~60% reduced
Foot paresthesia (been there for decades): 90% gone
Libido: Much higher
Small benign cyst on the back on my neck has reduced in size 40%
As of Aug 4 most of the above was still in place. I had a week of PEM just now, after a massive stress episode. However my previous PEM in April lasted 25 days; & before that serious stress could lay me out for weeks or months. Now gone.
I'd say that banishing the CFS + making oxalate, histamine & salicylate foods eatable again are the big gains in terms of being able to resume a normal life.