• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. K

    Hydroxocoblamin not converting to Adensoylcoblamin

    Hello all, I am taking a hydroxy b12 and Folinic acid lozenge along with plenty of riboflavin in the AM as I am MTHFR c677t double, but my MMA does not lower. I am also Comt ++ so methyl does not work for me/causes neurotransmitter issues. If I take an Adensoylcobalmin b12 lozenge in the PM...
  2. K

    Two Forms of B12 at Once = No Absorption?

    Hello all, After identifying my B12 deficiency via an MMA test (623) we tried methyl shots with methylfolate but found I was having neuropathy. Stopping both methyls cleared up the neuropathy and using an hydroxy b12 1000mcg/Folinic acid lozenge in the AM along with an Adensoyl b12 1000mcg...
  3. Pyrrhus

    B12: a simple 5-second poll for everyone

    This is a simple 5-second poll for anyone who has ever tried a B12 supplement in any form. Many thanks to everyone who responds! Please feel free to share your experience in more detail in a post.
  4. Hip

    Very noticeable improvements in brain fog using Dr Greg Russell-Jones's transdermal B12 oils (which provide a similar dose to B12 injections)

    For the last few months I have been using the methylcobalamin + adenosylcobalamin vitamin B12 transdermal oil developed by Dr Greg Russell-Jones in Australia, which he recommends for ME/CFS. This transdermal B12 oil has made very noticeable improvements in my brain fog and cognitive clarity...