I feel very bad

[linusbert]

can you share a shot of your lab?

 

[yellowspain]

can you share a shot of your lab?

What part or the analysis?

 

[linusbert]

What part or the analysis?

everything except your name, all labs. i mean the values.

 

[linusbert]

wow thats a very extensive blood works your doctor did , nice!

as far as i read this, you are not going to die anytime soon!

- electrolytes seam to be missing in those files?

- homocystein is in the midrange, thats fine, it indicates that your methylation isnt completely whacked otherwise it would be high
- also your red blood cells are in good shape, thats another indiciator that you do not have a B12/B6 or folat deficiency and also no significant iron or copper deficiency.

- your cholesterol values are very nice, you have 77 HDL thats really good, also the LDL is comparable low with 133, that means you have a ratio of LDL/HDL of below 2, this is really good,
the total cholesterol of ~220 is totally fine and you should not treat it. a isolated total cholesterol value says nothing. you need to watch at the ratios. there is LDL/HDL and TOTAL/HDL ratios, both of yours are really good. they even calculated it to 2,9 which is in the lower range.
also, the tryglicerides are low, so you definitely have no problem on the fat axis and no diabetes or no insulin resistence.
continue your fat intake as you do it right now, dont change it. and do NOT do take statins with those cholesterol values.
if your cholesterol is below 250 and your hdl/ldl ratio still that good. i would not even think about cholesterol.

- your cortisol and TSH values are higher, so you have high cortisol. i suppose your thyroid is in stress. could be infection maybe. or another stressor.
maybe getting some iodine and selenium to support thyroids is a good idea, but i dont know much about thyroids so other folks might have better info.

- your leucos seams to be higher in some tests, that indicates a current infection going on. could be a short time infection like a flu or something stomach/gut related, could also be something chronic.
thats where i suppose your vommitting came from.

- albumin in is normal high range, thats fine, i guess you are not short in proteins.

your blood work gives me no indicators for any methylation problems going on. you will not die due to methylation issues.


BUT i would have liked to see the magnesium, potassium, calcium, phosphorus, natrium, chloride values.


i would shift your focus away from methylation to other causes, like a infection.. or chronic infection even. or a food intolerance even.
do continue to support your methylation pathways but do not get obsessed about it.
but i would lower or cease supplementation until you get better and your body normalizes.

if your potassium is above 4 and your phosphor also in midrange+ i do not see your problem here at all.
btw, if i recall, freddd had low potassium values with his methylation issues. also his red cells were not in good shape. typical indicators of methylation issues you are missing.


EDIT:
i see that your leucocytes where elevated in urine, that could mean urinary tract infection. but also somewhere else possible.
you have somewhat protein in urine, can be normal due to diet. if it gets higher i would look for cause because it indicates kidney have some troubles.
could also be a sign of a high protein diet, like lots of meats or protein powder. your lower urine PH could be a sign of that because lots of purine rich meat metabolize acidic.

also your ferritin and iron values are normal but high, except ferritin thats elevated. that means your body stores of iron are full.
if you eat a lot of meat that could explain it. or if you take iron supplement.
but i know not much about iron panels and stuff, other people might have better explanation.


i would suppose with those values that you have lot of meat and proteins in your diet, maybe cut those down a bit. if you a carnivore, take a bit more fatty meat, not so much lean meat.

also ammonia could be a burden for your body, i would add something to your diet to lower or bind ammonia.
supplement with alpha-ketogluarat (akg).
there are also others but AKG binds it also in the guts.
ammonia overload could explain your vomiting too.

 

[yellowspain]

wow thats a very extensive blood works your doctor did , nice!

as far as i read this, you are not going to die anytime soon!

- electrolytes seam to be missing in those files?

- homocystein is in the midrange, thats fine, it indicates that your methylation isnt completely whacked otherwise it would be high
- also your red blood cells are in good shape, thats another indiciator that you do not have a B12/B6 or folat deficiency and also no significant iron or copper deficiency.

- your cholesterol values are very nice, you have 77 HDL thats really good, also the LDL is comparable low with 133, that means you have a ratio of LDL/HDL of below 2, this is really good,
the total cholesterol of ~220 is totally fine and you should not treat it. a isolated total cholesterol value says nothing. you need to watch at the ratios. there is LDL/HDL and TOTAL/HDL ratios, both of yours are really good. they even calculated it to 2,9 which is in the lower range.
also, the tryglicerides are low, so you definitely have no problem on the fat axis and no diabetes or no insulin resistence.
continue your fat intake as you do it right now, dont change it. and do NOT do take statins with those cholesterol values.
if your cholesterol is below 250 and your hdl/ldl ratio still that good. i would not even think about cholesterol.

- your cortisol and TSH values are higher, so you have high cortisol. i suppose your thyroid is in stress. could be infection maybe. or another stressor.
maybe getting some iodine and selenium to support thyroids is a good idea, but i dont know much about thyroids so other folks might have better info.

- your leucos seams to be higher in some tests, that indicates a current infection going on. could be a short time infection like a flu or something stomach/gut related, could also be something chronic.
thats where i suppose your vommitting came from.

- albumin in is normal high range, thats fine, i guess you are not short in proteins.

your blood work gives me no indicators for any methylation problems going on. you will not die due to methylation issues.


BUT i would have liked to see the magnesium, potassium, calcium, phosphorus, natrium, chloride values.


i would shift your focus away from methylation to other causes, like a infection.. or chronic infection even. or a food intolerance even.
do continue to support your methylation pathways but do not get obsessed about it.
but i would lower or cease supplementation until you get better and your body normalizes.

if your potassium is above 4 and your phosphor also in midrange+ i do not see your problem here at all.
btw, if i recall, freddd had low potassium values with his methylation issues. also his red cells were not in good shape. typical indicators of methylation issues you are missing.

My homocysteine has risen from 9 to 10, indicating that my cycle is not working properly. The deficiency of some nutrient is affecting my thyroid.

 

[linusbert]

my texts are sometimes very badly formulated, maybe read again in detail. i also did edit the text. i wrote multiple points which do not support a life threatening methylation problem.
homocysteine going from 9 to 10 , isnt saying much if in the next blood work it isnt going to 11. there is a statistical inaccuracy which can do such deviations. as the other parameters for methylation look fine (besides potassium and phosphor i did not see yet) i would not care.

BUT your electrolyte blood work is missing, you probably forgot it while scanning.

 

[almost]

My homocysteine has risen from 9 to 10, indicating that my cycle is not working properly.

That's not what this indicates.

The deficiency of some nutrient is affecting my thyroid.

There is no evidence of this. Your TSH is the only thing in your bloodwork that concerns me. But, a more comprehensive panel is necessary to approach any more detail on what is going on. Regardless, if there is dysfunction, iodine would be a first line conservative treatment. Very low doses, slowly increased.

 

[yellowspain]

That's not what this indicates.


There is no evidence of this. Your TSH is the only thing in your bloodwork that concerns me. But, a more comprehensive panel is necessary to approach any more detail on what is going on. Regardless, if there is dysfunction, iodine would be a first line conservative treatment. Very low doses, slowly increased.

How not? My homocysteine was 17, I started taking B9 and B12 and in a few days it went down to 9, until the vitamins stopped working and it went up to 10. I'm talking about facts.

 

[almost]

How not?

First of all, context. The text I quoted was your report of your value going from 9 to 10. Now, for the first time in this thread, you're introducing a prior value of 17. Note I was responding to the change from 9 to 10.

In the original, quoted context, that is not a concern because nothing in the body is static. Everything changes constantly. You likely would not have the same values on two consecutive tests. If you were to check your homocysteine every week on the same day for a year, you would find that the values fall in a range, probably looking very much like a normal distribution curve. A value of 9 or 10 is within most laboratory ranges also. It makes sense folate/b12 would lower it as it did.

I'm not clear on what you mean by "the vitamins stopped working."

 

[yellowspain]

First of all, context. The text I quoted was your report of your value going from 9 to 10. Now, for the first time in this thread, you're introducing a prior value of 17. Note I was responding to the change from 9 to 10.

In the original, quoted context, that is not a concern because nothing in the body is static. Everything changes constantly. You likely would not have the same values on two consecutive tests. If you were to check your homocysteine every week on the same day for a year, you would find that the values fall in a range, probably looking very much like a normal distribution curve. A value of 9 or 10 is within most laboratory ranges also. It makes sense folate/b12 would lower it as it did.

I'm not clear on what you mean by "the vitamins stopped working."

I mean that I managed to reactivate the cycle and then it stopped, returning me to the initial state. I suspect that I suffer from some induced deficiency.

 

[linusbert]

btw your blood work is still missing the electrolytes. you uploaded one page twice and probably forgot the other.

 

[yellowspain]

My electrolytes are right

 

[almost]

@yellowspain, this could explain a lot:

I think you need to find out what's behind this before worrying more about methylation.

 

[yellowspain]

@yellowspain, this could explain a lot:

View attachment 54289

I think you need to find out what's behind this before worrying more about methylation.

It is not the first time that a test shows that I have a urine infection and when the culture is done it comes out negative. It is what worries me least about the analysis.

 

[linusbert]

It is not the first time that a test shows that I have a urine infection and when the culture is done it comes out negative. It is what worries me least about the analysis.

i dont know, i would consider a round of antibiotics, and some natural things like ascorbic acid and there is another supplement called D-mannose which makes bacteria adhere to it instead of the bladder walls, so you will piss those out.
you also had some amounts of protein in your urine.
a bladder infection can go back to kidneys and cause more harm there.
you dont wanna have that, even if its not causative for your big issues now.

My electrolytes are right

if your electrolytes are right as well, means potassium higher than 4 , and phosphorus too not in the lower range, you can basically rule out any big methylation problems. because acute methylation problems will take those electrolytes down.
the homocysteine and shape and size of ERT might be somewhat delayed but electrolytes are acute.
if you still have doubt you might wanna call in freddd with a "mention" and ask his opinion.

 

[yellowspain]

The doctor has done a culture on me, I'm not going to take anything until he tells me to. I have no symptoms of infection and with some strips that you can test the urine at home, nothing comes out either. My problem is not a urine infection.


I can't have low electrolyte levels, because my methylation is blocked. I managed a small reset with b9/b12 until they stopped working.

 

[almost]

I have no symptoms of infection

• Title of thread: "I feel very bad"
• Urine leukocytes 16x top of lab range
• Bacteria seen in sample (doesn't mean they are bad)
• General malaise

• my body temperature has risen, almost having a fever.

• depression, vomiting and lack of apetite

• I am vomiting I think I am going to die

I disagree with your conclusion. I think you have plenty of signs. The negative lab culture ONLY means that there was nothing they culture for that was cultured. It DOES NOT mean you don't have an infection. I have dealt with this plenty with my animals.

There may be other reasons for your lab values, but I believe you are dismissing this too early. The other reasons aren't good either.

I managed a small reset with b9/b12 until they stopped working

Correlation does not mean causation. You may have contracted something at the same time you were experimenting with folate and B12. Doesn't mean the folate and B12 is behind all this.

 

[yellowspain]

The symptoms you mention are also caused by the thyroid.

 

[linusbert]

The doctor has done a culture on me, I'm not going to take anything until he tells me to. I have no symptoms of infection and with some strips that you can test the urine at home, nothing comes out either. My problem is not a urine infection.

whats your doctor saying to the methylation block? he any ideas?

Correlation does not mean causation. You may have contracted something at the same time you were experimenting with folate and B12. Doesn't mean the folate and B12 is behind all this.

actually, the pills could have been spoiled or bad in some ways.
i had pills which disturbed my guts, but its not been the vitamins, it was a specific product.
many folks do not take bad supplements serious, they lie around for years, get wet, be spoiled. some use rice and other starches as fillers, sometimes they are already molding before they are shipped.
quite a good point actually, the pills might be gone bad. or bad brand.
if b vitamins change color from bright orange to dark brown and do not flow anymore, its time to get rid of them.

 

[yellowspain]

Doctors don't know much about methylation and nutritional issues.For example, they did not know about the MTHFR mutation until I told them about it.
The only vitamins that they analyze in general are B9 and B12, but not the others.