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Prof. Akiko Iwasaki
https://x.com/VirusesImmunity/status/1844801167722709000
GWAS of #LongCOVID identified 3 loci pointing to immune and thrombo-inflammatory mechanisms
@ninaadsc
1) HLA-DQA1–HLA-DQB 2) ABO3) BPTF–KPAN2–C17orf58(1/)https://medrxiv.org/content/10.110
Excerpt:
This perspective article focuses on dorsal root ganglia (DRG) as potential fibromyalgia main pain source. Humans possess 31 pairs of DRG lying along the spine. These ganglia have unique anatomical and physiological features. During development, DRG are extruded from the central nervous...
https://www.earthclinic.com/cures/chronic_fatigue_syndrome.html
https://www.earthclinic.com/cures/treatment-for-fibromyalgia-pain-symptoms.html
We can help each others by adding cure that helped you on this website, the cure for chronic fatigue on this website is sodium carbonate, and sodium...
This paper is facing some opposition.
The paper in question: Long COVID: a new word for naming fibromyalgia?
The problem was called out by:
and https://twitter.com/resiapretorius
Peer review (as we have noted) can be an interesting process, especially if the authors suggest their friends...
Whole-Body Vibration Training on Oxidative Stress Markers, Irisin Levels, and Body Composition in Women with Fibromyalgia: A Randomized Controlled Trial
Abstract
(1) Background: Mitochondrial dysfunction and redox imbalance seem to be involved in fibromyalgia (FM) pathogenesis. The results of...
Lately, I have to avoid sudden exposures to frigid temps, such as in briefly opening a door or window and letting in a blast of arctic air. What happens is that I will start to shiver, then my entire body will go into a painful spasm.
I first noticed this about five years ago, when we were...
I´m very glad that Cort Johnson published this very good article.
At the same time it is very frustrating that doctors in Germany refuse (for whatever reason) to test VLCFA even though I delivered previous results (tested in USA 2018) for elevated phytanic acid.
I mentioned " New article on...
Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia
Abstract
Background
Catechol-O-methyltransferase (COMT) has been shown to influence clinical pain, descending modulation, and exercise-induced symptom...
Is CFS the same illness as fibromyalgia: evaluating the ‘single syndrome’ hypothesis (Abbi and Natelson, 2012)
https://doi.org/10.1093/qjmed/hcs156
I noticed that this paper from 2012 hasn't been posted yet, so here it is.
Important Note: This paper was published before the modern diagnostic...
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes
Abstract
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has...
AAPT Diagnostic Criteria for Fibromyalgia (Arnold et al., 2018)
https://doi.org/10.1016/j.jpain.2018.10.008
Os critérios diagnósticos atuais para fibromialgia foram definidos em 2018 por um grupo de trabalho internacional de clínicos e pesquisadores com experiência em fibromialgia. O processo...
AAPT Diagnostic Criteria for Fibromyalgia (Arnold et al., 2018)
https://doi.org/10.1016/j.jpain.2018.10.008
Los criterios diagnósticos actuales para la fibromialgia fueron definidos en 2018 por un grupo de trabajo internacional formado por clínicos e investigadores expertos en fibromialgia. El...
Active Herpes Simplex Virus Found in FM Patients’ Guts
A New Virus for Fibromyalgia (and ME/CFS?)
Despite Pridgen’s success at getting a large trial together, we’ve been missing a significant piece of data – evidence that the herpes simplex viruses he’s stated that he believes are causing FM...
Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia (Verma et al., 2021)
https://doi.org/10.1097/j.pain.0000000000002498
Main points:
The authors investigated the Natural Killer (NK) cells of fibromyalgia patients.
The authors found low numbers of NK...
Summary: New research has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body. The results show that fibromyalgia is a disease of the immune system, rather than the currently...
Fibromyalgia: Diagnostic Criteria
In 1995, as an undergraduate, I was asked to put together a brief review of the literature on fibromyalgia. At the time, I knew little about fibromyalgia and absolutely nothing about ME/cfs. In my brief review, which I recently unearthed, I noted that there...
The Role of the Vagus Nerve in Fibromyalgia Syndrome
Daniel F Martins 1, et al.
Neurosci Biobehav Rev
2021 Oct 25;S0149-7634(21)00463-2.
PMID: 34710514 DOI: 10.1016/j.neubiorev.2021.10.021
Abstract
Fibromyalgia (FM) syndrome is a common illness characterized by chronic widespread pain, sleep...
Authors: Julius H Bourke, Theresa Wodehouse, Lucy V Clark, Elena Constantinou, Bruce L Kidd, Richard Langford, Vivek Mehta, Peter D White
Published: November 2021
Published in: Journal of Psychosomatic Research
PMID: 34600309
doi: 10.1016/j.jpsychores.2021.110624
Abstract
Passive transfer of fibromyalgia symptoms from patients to mice
I'm always dubious about symptom evaluation in mice. I guess it adds weight to the autoimmune theory for both FM and likely ME/CFS. But I believe some ME/CFS patients have had plasmapharesis without success, is that true?
The pope is not a scientist, of course, but I hear he has a pretty decent following so this should be good news!
Pope calls for more attention to fibromyalgia
https://aleteia.org/2021/05/09/pope-calls-for-more-attention-to-fibromyalgia/
Piggybacking off https://www.mechanicalbasis.org/ + https://forums.phoenixrising.me/threads/have-you-ruled-out-chiari-or-craniocervical-instability-cci-as-a-cause-of-your-cfs.56908/#post-945253 , a story of a man that suffered CFS alongside POTS...I'm inspired to sort out my body, especially...
Characterization of dermal skin innervation in fibromyalgia syndrome
Dimitar Evdokimov,
Philine Dinkel,
Johanna Frank,
Claudia Sommer,
Nurcan Üçeyler
Published: January 13, 2020
Abstract
Introduction
We characterized dermal innervation in patients with fibromyalgia...
A new study published in May 2019 finds preliminary evidence that fibromyalgia might be due to insulin resistance:
Is insulin resistance the cause of fibromyalgia? A preliminary report
The study found highly significant association between fibromyalgia and glycosylated haemoglobin (HbA1c)...
PET imaging studies reveal elevated glial activation, correlation with fatigue levels
The results from both centers found that glial activation in several regions of the brains of fibromyalgia patients was significantly greater than it was in control participants. Compared to the MGH team's...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344444/#
J Pain Res. 2017; 10: 515–525.
Published online 2017 Mar 3. doi: 10.2147/JPR.S128508
PMCID: PMC5344444
Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied...
Hi, this is just a general discussion about my general health and a query as to whether I now better fit a diagnosis of fibromyalgia over ME/CFS.
Initially my symptoms were dominated by nausea, vomiting, swollen lymph nodes and general weakness - my guess is that this was an "acute phase" which...