fibromyalgia

  1. SWAlexander

    Much-needed data on the genetics of #longCOVID in a new preprint by @23andMeResearch

    Read Prof. Akiko Iwasaki https://x.com/VirusesImmunity/status/1844801167722709000 GWAS of #LongCOVID identified 3 loci pointing to immune and thrombo-inflammatory mechanisms @ninaadsc 1) HLA-DQA1–HLA-DQB 2) ABO3) BPTF–KPAN2–C17orf58(1/)https://medrxiv.org/content/10.110
  2. SWAlexander

    Dorsal root ganglia: fibromyalgia pain factory?

    Excerpt: This perspective article focuses on dorsal root ganglia (DRG) as potential fibromyalgia main pain source. Humans possess 31 pairs of DRG lying along the spine. These ganglia have unique anatomical and physiological features. During development, DRG are extruded from the central nervous...
  3. SWAlexander

    MCAS activated by Long COVID or PACS or by MIS-C or PIMS and MCAS activated by Vaccines or by Post Vaccine Syndrome: CRITERIA FOR CLINICAL DIAGNOSIS

    Introduction: Also for patients diagnosed with ME/CFS, Fibromyalgia, Lyme, EBV, Morgellons diseases, Asthma, Allergies, MCS, Tinnitus, POTS, Dysautonomia, Ehlers-Danlos Syndrome (EDS), Small Fiber Neuropathy (SNF), Restless Legs Syndrome (RLS), Burning Mouth Syndrome, Panic Attacks, Anxiety...
  4. Y

    Do you know about earthclinic.com

    https://www.earthclinic.com/cures/chronic_fatigue_syndrome.html https://www.earthclinic.com/cures/treatment-for-fibromyalgia-pain-symptoms.html We can help each others by adding cure that helped you on this website, the cure for chronic fatigue on this website is sodium carbonate, and sodium...
  5. SWAlexander

    Long COVID: a new word for naming fibromyalgia?

    This paper is facing some opposition. The paper in question: Long COVID: a new word for naming fibromyalgia? The problem was called out by: and https://twitter.com/resiapretorius Peer review (as we have noted) can be an interesting process, especially if the authors suggest their friends...
  6. C

    Whole-Body Vibration Training on Oxidative Stress Markers, Irisin Levels, and Body Composition in Women with Fibromyalgi... (dos Santos et al, 2023)

    Whole-Body Vibration Training on Oxidative Stress Markers, Irisin Levels, and Body Composition in Women with Fibromyalgia: A Randomized Controlled Trial Abstract (1) Background: Mitochondrial dysfunction and redox imbalance seem to be involved in fibromyalgia (FM) pathogenesis. The results of...
  7. C

    Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia... (Nepotchatykh et al, 2023)

    Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia and comorbid conditions Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and fibromyalgia (FM) are two chronic complex diseases with overlapping symptoms affecting multiple...
  8. belize44

    When It's Cold

    Lately, I have to avoid sudden exposures to frigid temps, such as in briefly opening a door or window and letting in a blast of arctic air. What happens is that I will start to shiver, then my entire body will go into a painful spasm. I first noticed this about five years ago, when we were...
  9. SWAlexander

    ME/CFS, Fibromyalgia, and Long COVID – the “Metabolic Derangement” Diseases?

    I´m very glad that Cort Johnson published this very good article. At the same time it is very frustrating that doctors in Germany refuse (for whatever reason) to test VLCFA even though I delivered previous results (tested in USA 2018) for elevated phytanic acid. I mentioned " New article on...
  10. C

    Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and F... (Polli et al, 2022)

    Genetic and epigenetic regulation of Catechol-O-methyltransferase in relation to inflammation in chronic fatigue syndrome and Fibromyalgia Abstract Background Catechol-O-methyltransferase (COMT) has been shown to influence clinical pain, descending modulation, and exercise-induced symptom...
  11. Pyrrhus

    Is CFS the same illness as fibromyalgia: evaluating the ‘single syndrome’ hypothesis (Abbi and Natelson, 2012)

    Is CFS the same illness as fibromyalgia: evaluating the ‘single syndrome’ hypothesis (Abbi and Natelson, 2012) https://doi.org/10.1093/qjmed/hcs156 I noticed that this paper from 2012 hasn't been posted yet, so here it is. Important Note: This paper was published before the modern diagnostic...
  12. C

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid prote… (Schutzer et al, 2022)

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has...
  13. Pyrrhus

    Fibromialgia: Critérios de diagnóstico em português

    AAPT Diagnostic Criteria for Fibromyalgia (Arnold et al., 2018) https://doi.org/10.1016/j.jpain.2018.10.008 Os critérios diagnósticos atuais para fibromialgia foram definidos em 2018 por um grupo de trabalho internacional de clínicos e pesquisadores com experiência em fibromialgia. O processo...
  14. Pyrrhus

    Fibromialgia: Criterios de diagnóstico en español

    AAPT Diagnostic Criteria for Fibromyalgia (Arnold et al., 2018) https://doi.org/10.1016/j.jpain.2018.10.008 Los criterios diagnósticos actuales para la fibromialgia fueron definidos en 2018 por un grupo de trabajo internacional formado por clínicos e investigadores expertos en fibromialgia. El...
  15. SWAlexander

    A Herpesvirus for Fibromyalgia?

    Active Herpes Simplex Virus Found in FM Patients’ Guts A New Virus for Fibromyalgia (and ME/CFS?) Despite Pridgen’s success at getting a large trial together, we’ve been missing a significant piece of data – evidence that the herpes simplex viruses he’s stated that he believes are causing FM...
  16. Pyrrhus

    Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia (Verma et al., 2021)

    Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia (Verma et al., 2021) https://doi.org/10.1097/j.pain.0000000000002498 Main points: The authors investigated the Natural Killer (NK) cells of fibromyalgia patients. The authors found low numbers of NK...
  17. SWAlexander

    Fibromyalgia likely the result of autoimmune problems

    Summary: New research has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body. The results show that fibromyalgia is a disease of the immune system, rather than the currently...
  18. Pyrrhus

    Fibromyalgia (FM): Diagnostic Criteria

    Fibromyalgia: Diagnostic Criteria In 1995, as an undergraduate, I was asked to put together a brief review of the literature on fibromyalgia. At the time, I knew little about fibromyalgia and absolutely nothing about ME/cfs. In my brief review, which I recently unearthed, I noted that there...
  19. Shanti1

    The Role of the Vagus Nerve in Fibromyalgia Syndrome

    The Role of the Vagus Nerve in Fibromyalgia Syndrome Daniel F Martins 1, et al. Neurosci Biobehav Rev 2021 Oct 25;S0149-7634(21)00463-2. PMID: 34710514 DOI: 10.1016/j.neubiorev.2021.10.021 Abstract Fibromyalgia (FM) syndrome is a common illness characterized by chronic widespread pain, sleep...
  20. nerd

    Central sensitisation in chronic fatigue syndrome and fibromyalgia; a case control study

    Authors: Julius H Bourke, Theresa Wodehouse, Lucy V Clark, Elena Constantinou, Bruce L Kidd, Richard Langford, Vivek Mehta, Peter D White Published: November 2021 Published in: Journal of Psychosomatic Research PMID: 34600309 doi: 10.1016/j.jpsychores.2021.110624 Abstract
  21. nerd

    Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls

    Groven N, Reitan SK, Fors EA, Guzey IC. Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. Psychoneuroendocrinology. 2021 Sep;131:105287. doi: 10.1016/j.psyneuen.2021.105287. Epub 2021 May 27. PMID: 34090138. Abstract
  22. WantedAlive

    Fibromyalgia: transfer of patient IgG antibodies produce FM symptoms in mice

    Passive transfer of fibromyalgia symptoms from patients to mice I'm always dubious about symptom evaluation in mice. I guess it adds weight to the autoimmune theory for both FM and likely ME/CFS. But I believe some ME/CFS patients have had plasmapharesis without success, is that true?
  23. Pyrrhus

    Pope calls for more attention to fibromyalgia

    The pope is not a scientist, of course, but I hear he has a pretty decent following so this should be good news! Pope calls for more attention to fibromyalgia https://aleteia.org/2021/05/09/pope-calls-for-more-attention-to-fibromyalgia/
  24. W

    Inspired to find what my problem is and need guidance. I've felt like death my entire life, the rare times I didn't tell me this isn't normal.

    Piggybacking off https://www.mechanicalbasis.org/ + https://forums.phoenixrising.me/threads/have-you-ruled-out-chiari-or-craniocervical-instability-cci-as-a-cause-of-your-cfs.56908/#post-945253 , a story of a man that suffered CFS alongside POTS...I'm inspired to sort out my body, especially...
  25. pattismith

    Characterization of dermal skin innervation in fibromyalgia syndrome 2020

    Characterization of dermal skin innervation in fibromyalgia syndrome Dimitar Evdokimov, Philine Dinkel, Johanna Frank, Claudia Sommer, Nurcan Üçeyler Published: January 13, 2020 Abstract Introduction We characterized dermal innervation in patients with fibromyalgia...
  26. Hip

    Is insulin resistance the cause of fibromyalgia? In a subset of fibromyalgia patients, metformin dramatically improved pain

    A new study published in May 2019 finds preliminary evidence that fibromyalgia might be due to insulin resistance: Is insulin resistance the cause of fibromyalgia? A preliminary report The study found highly significant association between fibromyalgia and glycosylated haemoglobin (HbA1c)...
  27. Jackb23

    Research teams find widespread neuroinflammation in the brains of fibromyalgia patients

    PET imaging studies reveal elevated glial activation, correlation with fatigue levels The results from both centers found that glial activation in several regions of the brains of fibromyalgia patients was significantly greater than it was in control participants. Compared to the MGH team's...
  28. H

    Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344444/# J Pain Res. 2017; 10: 515–525. Published online 2017 Mar 3. doi: 10.2147/JPR.S128508 PMCID: PMC5344444 Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied...
  29. B

    Identification of a MicroRNA Signature for the Diagnosis of Fibromyalgia

    Spain: Universidad Católica de Valencia "San Vicente Mártir".
  30. Legendrew

    Fibromyalgia or ME/CFS?

    Hi, this is just a general discussion about my general health and a query as to whether I now better fit a diagnosis of fibromyalgia over ME/CFS. Initially my symptoms were dominated by nausea, vomiting, swollen lymph nodes and general weakness - my guess is that this was an "acute phase" which...
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