me/cfs

  1. SWAlexander

    **EXCLUSIVE** Biomarker Breakthrough?

    Listen to Bhupesh Prusty interview in the link. https://www.tlcsessions.net/episodes/episode-58-breakthrough-biomarker- For the past three years we have suffered with a myriad of over 200 symptoms. Every expert that we have spoken to has either treated the symptoms whilst acknowledging the...
  2. SWAlexander

    Different risk factors distinguish myalgic encephalomyelitis/chronic fatigue syndrome from severe fatigue

    Sorry, if this is already posted. Abstract Fatigue is a common reason that patients seek medical care. Only a fraction of these patients meet criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). To determine if ME/CFS is just a more extreme form of fatigue, or a...
  3. SWAlexander

    Stress-Induced Transcriptomic Changes in Females with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Reveal Disrupted Immune Signatures

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, complex multi-organ illness characterized by unexplained debilitating fatigue and post-exertional malaise (PEM), which is defined as a worsening of symptoms following even minor physical or mental exertion. Our...
  4. SWAlexander

    ME/CFS, FM, RA, SS, POTS, PVACS, Lyme:

    This is the first complete research that confirms my long-standing theory. This is a long paper, though reading is worth it. ME/CFS, FM, RA, SS, POTS, PVACS, Lyme: THERAPEUTIC TEST AND FIRST TREATMENT REGIME, WITH FIBRINOLYTICS AND FAMOTIDINE FOR PATIENTS WITH CHRONIC FATIGUE AND/OR PAIN TO...
  5. SWAlexander

    Long COVID: major findings, mechanisms and recommendations

    It is a very extensive study. Abstract Long COVID is an often debilitating illness that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms have been identified with impacts on multiple organ systems. At least 65 million...
  6. SWAlexander

    Converging Evidence of Similar Symptomatology of ME/CFS and PASC Indicating Multisystemic Dyshomeostasis

    Abstract The purpose of this article is to review the evidence of similar symptomatology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute sequelae of SARS-CoV-2 infection (PASC). Reanalysis of data from a study by Jason comparing symptom reports from two groups of...
  7. SWAlexander

    Orthostatic Intolerance after COVID-19 Infection: Is Disturbed Microcirculation of the Vasa Vasorum of Capacitance Vessels the Primary Defect?

    Abstract Following COVID-19 infection, a substantial proportion of patients suffer from persistent symptoms known as Long COVID. Among the main symptoms are fatigue, cognitive dysfunction, muscle weakness and orthostatic intolerance (OI). These symptoms also occur in myalgic...
  8. SWAlexander

    Genetic risk factors for ME/CFS identified using combinatorial analysis

    Published: 14 December 2022 Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease that lacks known pathogenesis, distinctive diagnostic criteria, and effective treatment options. Understanding the genetic (and other) risk factors...
  9. SWAlexander

    Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

    Abstract Background Muscle fatigue and pain are key symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although the pathophysiology is not yet fully understood, there is ample evidence for hypoperfusion which may result in electrolyte imbalance and sodium overload in...
  10. SWAlexander

    ME/CFS, Fibromyalgia, and Long COVID – the “Metabolic Derangement” Diseases?

    I´m very glad that Cort Johnson published this very good article. At the same time it is very frustrating that doctors in Germany refuse (for whatever reason) to test VLCFA even though I delivered previous results (tested in USA 2018) for elevated phytanic acid. I mentioned " New article on...
  11. SWAlexander

    PATIENT-LED RESEARCH COLLABORATIVE ANNOUNCES $4.8 MILLION IN BIOMEDICAL RESEARCH AWARDS FOR LONG COVID AND ASSOCIATED CONDITIONS

    The Patient-Led Research Collaborative’s Patient-Led Research Fund announced $4.8 million in biomedical research awards today, funding 9 research projects in Long COVID, ME/CFS, dysautonomia, and associated conditions. This fund and awarded projects are distinctly meaningful for four major...
  12. frozenborderline

    Indigenous people of siberia tolerate tick borne infections better, have more resilience

    https://drive.google.com/file/d/1BBLa4FTv3LgBoZJNOtU9RQeraZ__026G/view?usp=drivesdk Interesting. Could validate environmental/dual factor theory of @Hip or it could be their microbiome or some epigenetic factor.
  13. frozenborderline

    [Indie Band] Belle and Sebastian Frontman: "Living with ME makes me feel like a non person "

    https://www.independent.co.uk/news/uk/myalgic-encephalomyelitis-scottish-parliament-scotland-msps-holyrood-b2177301.html He's also an OMF ambassador. He's one of one of most prominent famous people with our illness. Albeit more mild than a lot of us bedridden folks. But apparently early on he...
  14. SWAlexander

    Autoantibody determination in chronic fatigue syndrome (CFS)

    This is a google auto translation: Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a common and severe multisystem disease. A defined cause could not be found so far. What is clear, however, is that dysregulation of the immune system, the hormone system, the...
  15. SWAlexander

    1934 Los Angeles atypical polio outbreak

    Thank you for pointing it out. Finally!!! I have been saying for years PPS is (part of) ME/CFS. I was laughed at by every doctor telling me "you have no medical credentials." But, I have had all related symptoms since the age of 5 y old. The 1934 Los Angeles County General Hospital epidemic...
  16. frozenborderline

    Long covid has forced a reckoning for one of medicines most neglected diseases

    https://www.theatlantic.com/health/archive/2022/09/mecfs-chronic-fatigue-syndrome-doctors-long-covid/671518/ An article by Ed Yong, about how long covid is forcing people to address the situation with me/cfs. I'm not sure he's right about that but it's worth a read and he is getting our...
  17. SWAlexander

    New study links 14 genes to ME/CFS

    A study has analysed existing genetic data in a new way to link 14 genes to ME/CFS and identify many patient subgroups. If the new approach pans out, it could transform ME research and turbocharge the development of treatments. Paper: Genetic Risk Factors for ME/CFS Identified Using...
  18. SWAlexander

    Researchers say they have found a link in the pathology between long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

    Article: Researchers say they have found a link in the pathology between long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Key points: Griffith University researchers say their findings could help to treat those suffering from long COVID A woman with chronic fatigue...
  19. frozenborderline

    NIH misallocating funds and moving slow on Long covid research

    https://www.statnews.com/2022/03/29/nih-long-covid-sluggish-study/
  20. frozenborderline

    Looking for podcast participants for my ME/CFS related podcast

    looking for podcast participants Potentially upsetting Looking for people to be interviewed on a podcast: The most interesting things I'd like to talk about ir type of guests : 1. People who have had some kind of experience with environmental factors in their illness People who have done some...
  21. gauche

    Diagnostic for reduced calcium in cells

    Hey folks, As we know, there's a lot of chatter about links between ME/CFS and long COVID. However, today I was surprised to read that a research team in QLD are looking into whether their ME/CFS diagnostic test (yes, diagnostic test) and treatment (double yes) will also work for long COVID...
  22. SWAlexander

    Eye movements may be key to chronic fatigue syndrome diagnosis

    25 March 2022 Oculomotor testing in the lab. A Monash Central Clinical School scientist has been awarded $180,000 over three years to develop a way to help diagnose myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Associate Professor Joanne...
  23. SWAlexander

    Chronic Fatigue Syndrome: The Need to Raise Awareness

    Excerpt: Most doctors and people with chronic fatigue syndrome don't know the name of this syndrome or anything else about it. The CDC estimates that 90% of people with ME/CFS aren't diagnosed by a health care professional. “Of all the people who completed the survey, only 46% had ever heard...
  24. frozenborderline

    An Open Letter to the Open Medicine Foundation, by Kaylin Jones

    https://openletteropenmedicinefoundation.com/an-open-letter-to-the-open-medicine-foundation-by-kaylin-jones/ Another person asking the OMF to look into mold or environmental toxins in ME/CFS. So far they haven't responded. But lets keep trying. If anyone else has experienced environmental...
  25. SWAlexander

    A new part of my ME/CFS diagnosis: "CYP3A4"

    Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring Abstract Cytochrome P450 (CYP) 3A4 is the most abundant enzyme of CYPs in the liver and gut that...
  26. frozenborderline

    What outlets do we have to publish pieces of art or writing about this illness and theology or spirituality, or just any art about it?

    What outlets besides our own blogs can we publish art specific for ME/CFS peolle or people with chronic illness? Omf rejected a poem I wrote for supposedly being too dark, it made me very sad and made me think I cant really connect with people in the me/cfs community. Bc this particular poem...
  27. SWAlexander

    Expertise in post-viral illness and ME/CFS

    Expert Virtual Care for Long COVID One in three people who have been ill with COVID develop long term health effects including disabling fatigue, cognitive and mood disorders, and many other symptoms. We can help. RTHM brought on post-viral illness & ME/CFS expert Jennifer M. Curtin MD from...
  28. SWAlexander

    New OMF funded paper: "Lessons From Heat Stroke for Understanding ME/CFS"

    On behalf of Open Medicine Foundation, I'm pleased to share that a new research publication, authored by myself and colleagues, has been published in Frontiers in Neurology: “Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.”...
  29. frozenborderline

    Polybio (small org founded by michael vanelzakker and amy proal) has announced first cci study in ME/CFS

    Here's the tweet announcement. I expect lots of discussing about this , its very exciting news , but I am concerned they are not using upright mri if I read btwn the lines. (Upright mris in 7Tesla dont exist I think, not even in 3 tesla) Anyway I will post my thoughts about this in a...