Have you tried CBD oil? Any effects? Or LDN? Did LDN have any effects? LDN seems to have helped some 70% of CFS patients according a retrospective study. It has effects partly similar to that of beta-caryophyllene in cell membrane. There is natural copaiba oil and refined (isolate). Which one you used? They are not the same.
I take THC oil for sleep, it helps with sleep but not ME. Started it much more recently than the copaiba though. Never tried CBD oil.
Tried LDN only for a few weeks back when I first became severe. Gave me worse brain fog and messed with my sleep so I stopped it. I will probably retry it soon. I don't think it has actually helped 70 % of people when you look at the reports here but I'm not sure.
This is the one I've used.