Mary
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Thanks @Jyoti - That must be a bit maddening, to have such a good response first time around only to have it diminish. It seems to happen with a lot of things that I try! I am going to add the copaiba oil to my list of things to try. Right now I'm experimenting with a CBD product called Delta 8 for sleep (you can't get THC in Texas) and it is helping, though I'm afraid its effect may diminish over time. But one thing at a time -@Mary -- I did mix it at 1:15 or 1:16 with a carrier oil. Then I put a few drops (5ish) under my tongue every couple of hours over the course of the day. The second time I tried it, I had much diminished response and sort of drifted off taking it. I definitely had a notable response the first time around, but it was diminished when I returned after a break. I still think it is interesting and have it on my shelf of supplements--the one I look at every morning, noon and night--and will likely do some more experimenting once I am done with several other trials I have lined up.
The review linked above by @kangaSue is quite interesting - it has a good section on beta-caryophyllene (that is a hard word to spell! ) - I'd never thought of essential oils as having any real effect or benefit before reading it: A Systematic Review of Essential Oils and the Endocannabinoid System: A Connection Worthy of Further Exploration (hindawi.com)