That was great, what an outstanding discussion.
Fortunately, the folks at Patient-led Research have pre-published a fairly comprehensive picture of the symptoms in Long Covid:
Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and
Although the above article, which was written by Long Covid patients their selves, probably remains the most authoritative description of Long Covid, there have been a few other publications of note:Characterizing long COVID in an international cohort: 7 months of symptoms and their impact (Davis et al., 2021)
At 12 months after acute infection, COVID-19 survivors were still suffering from symptoms identified at shorter follow-up, and the most frequent symptoms included fatigue, pain, and sleep disorders. A more severe impairment in the acute phase did not seem to predict more severe complications.
We present a longitudinal, prospective analysis of health consequences in patients who initially presented with no or minor symptoms of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection. Hence, we focus on mild COVID-19 in non-hospitalised patients. [...] We observed 442 and 353 patients over four and seven months after symptom onset, respectively. Four months post SARS-CoV-2 infection, 8.6% (38/442) of patients presented with shortness of breath, 12.4% (55/442) with anosmia, 11.1% (49/442) with ageusia and 9.7% (43/442) with fatigue. At least one of these characteristic symptoms was present in 27.8% (123/442) and 34.8% (123/353) at month 4 and 7 post-infection, respectively. A lower baseline level of SARS-CoV-2 IgG, anosmia and diarrhoea during acute COVID-19 were associated with higher risk to develop long-term symptoms.
This systematic review and meta‐analysis aims to identify studies assessing the long‐term effects of COVID‐19. LitCOVID and Embase were searched to identify articles with original data published before the 1st of January 2021, with a minimum of 100 patients. [...] A total of 18,251 publications were identified, of which 15 met the inclusion criteria. The prevalence of 55 long‐term effects was estimated, 21 meta‐analyses were performed, and 47,910 patients were included (age 17–87 years). The included studies defined long‐COVID as ranging from 14 to 110 days post‐viral infection. It was estimated that 80% of the infected patients with SARS‐CoV‐2 developed one or more long‐term symptoms. The five most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%).
What do you mean with people being wrongly medicated with Aspirin?Unfortunately I could not find extensive explanation about von Willebrand or Faktor-V-Leiden-Mutation exept in Austria guidelines. It appears to be a fact that most people had never a Factor test and been consequently and often wrongly medicated - example Aspirin. To understand the difference and details about clots I see a Hematologist as the only solution.
If you like to read and have google translator. https://www.gesundheit.gv.at/labor/laborwerte/blutgerinnung/faktor-v-leiden-mutation
Microclots are resistant to Aspirin. https://pubmed.ncbi.nlm.nih.gov/34425843/ "....might be due to the presence of persistent circulating plasma microclots that are resistant to fibrinolysis."What do you mean with people being wrongly medicated with Aspirin?
Now published in the Lancet:
Characterizing long COVID in an international cohort: 7 months of symptoms and their impact (Davis et al., 2021)
Although the above article, which was written by Long Covid patients their selves, probably remains the most authoritative description of Long Covid, there have been a few other publications of note:
• Fatigue and cognitive impairment are amongst the most common and debilitating symptoms of post-COVID-19 syndrome.
• Approximately 1 in 3 individuals experienced fatigue 12 or more weeks following COVID-19 diagnosis.
• Approximately 1 in 5 individuals exhibited cognitive impairment 12 or more weeks following COVID-19 diagnosis.
• Narrative synthesis revealed elevations in proinflammatory markers and considerable functional impairment in a subset of individuals.
The literature search yielded 10,979 studies, and 81 studies were selected for inclusion. The fatigue meta-analysis comprised 68 studies, the cognitive impairment meta-analysis comprised 43 studies, and 48 studies were included in the narrative synthesis. Meta-analysis revealed that the proportion of individuals experiencing fatigue 12 or more weeks following COVID-19 diagnosis was 0.32 (95% CI, 0.27, 0.37; p < 0.001; n = 25,268; I2=99.1%). The proportion of individuals exhibiting cognitive impairment was 0.22 (95% CI, 0.17, 0.28; p < 0.001; n = 13,232; I2=98.0). Moreover, narrative synthesis revealed elevations in proinflammatory markers and considerable functional impairment in a subset of individuals.
This piece explores data suggesting that long Covid is contributing to record high numbers of unfilled jobs by keeping millions of people from getting back to work.
With 10.6 million unfilled jobs across the country, the months-long labor shortage is weighing on the U.S. economy. Small businesses are losing money due to understaffing. Local governments are struggling to fill jobs. Investors are spooked, and corporate profits are taking a hit.
Economists have proposed a number of explanations, including a decline in workers’ willingness to tolerate low pay and poor working conditions, lack of access to child care, concerns about contracting COVID-19, higher household savings, and demographic and immigration trends. Yet they rarely mention long Covid.
As Lisa McCorkell, co-founder of the long-Covid-focused Patient-Led Research Collaborative, told Brookings, “Until we have data from a representative sample that accurately capture the extent of the impacts to the labor force, economists and policymakers are likely not going to consider long Covid an economic issue or recognize it for the mass disabling event it is.”
i don't think that explains loss of collagen in the body, either - my fingerprints gone, other body parts decrepit.
i go by symptoms first. I do believe in tests, but my sysmptoms are higher priority, if that makes sense.
There may be another way to keep cal-mag in your blood. If someone knows of another way, I'd like to hear it.