• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. SWAlexander

    MCAS activated by Long COVID or PACS or by MIS-C or PIMS and MCAS activated by Vaccines or by Post Vaccine Syndrome: CRITERIA FOR CLINICAL DIAGNOSIS

    Introduction: Also for patients diagnosed with ME/CFS, Fibromyalgia, Lyme, EBV, Morgellons diseases, Asthma, Allergies, MCS, Tinnitus, POTS, Dysautonomia, Ehlers-Danlos Syndrome (EDS), Small Fiber Neuropathy (SNF), Restless Legs Syndrome (RLS), Burning Mouth Syndrome, Panic Attacks, Anxiety...
  2. Hip

    Viral proteins from SARS-CoV-2 mimic human immune peptides, causing exaggerated proinflammatory immune responses

    Article: "Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes Study: Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Whether these SARS-CoV-2 fragments imitating peptides from the...
  3. SWAlexander

    Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation

    This is a very long paper. The most important part: Excerpt: Discussion: PCS patients with CFS exhibited a more severely impaired retinal microvascular integrity in our cohort. Even though this association was weaker after controlling for confounders, this aligns with recent findings...
  4. SWAlexander


    Abstract and Figures MANAGEMENT OF THE PATIENT WITH PERSISTENT SYMPTOMS POST ACUTE COVID (for Post Acute COVID Syndrome, PACS, Long COVID or Chronic COVID; Post-Vaccine COVID Syndrome). DIAGNOSIS AND TREATMENT. In this document, the proposal for the management of patients with Persistent...
  5. SWAlexander

    Striking Drop in Stress Hormone Predicts Long Covid in Study

    Cortisol could be used with other biomarkers for diagnosis Research identifies three potential causes of chronic symptoms Striking decreases in the stress hormone cortisol were the strongest predictor for who develops long Covid in new research that identified several potential drivers of the...
  6. SWAlexander

    Researchers say they have found a link in the pathology between long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

    Article: Researchers say they have found a link in the pathology between long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Key points: Griffith University researchers say their findings could help to treat those suffering from long COVID A woman with chronic fatigue...
  7. SWAlexander

    Common viruses may be triggering the onset of Alzheimer's disease

    Shingles infection may activate dormant neurological herpes viruses, causing inflammation and accumulation of Alzheimer's associated proteins in the brain Date: August 2, 2022 Source: Tufts University Summary...
  8. leokitten

    Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19. Karagiannis et al, Nature (2022)

  9. Hip

    Those who have had COVID: did you experience anhedonia afterwards (reduced ability to find enjoyment from activities)?

    Has anyone found they are suffering from increased anhedonia after getting COVID? Anhedonia is defined as a reduce ability to derive pleasure or reward from activities that you previously found enjoyable. Anhedonia is caused by a dysfunction in the pleasure circuits of the brain, so that these...
  10. E

    Genetic polymorphism of MTHFR C677 T may modulate the incidence and severity of COVID-19

    COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence https://pubmed.ncbi.nlm.nih.gov/34061414/ Abstract Background: Homocysteine assessment has been proposed as a potential predictive biomarker for the severity of...
  11. SWAlexander

    Β-Amyloid Deposits in Young COVID Patients

    Abstract A 58-year-old woman who died of COVID infection was included as a control subject in an ongoing autopsy study of the neuropathology of military traumatic brain injury (TBI). An immunohistochemical stain for β-amyloid done only because that stain is performed on all the cases in the...
  12. SWAlexander

    Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

    Abstract A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to age- and gender-matched recovered individuals without LC, unexposed...
  13. frozenborderline

    My plan for surviving covid, plus vaccine dillemmas

    I need to figure out how to answer the question of if the existing vaccines side effects are worse than long covid sequelae from omicron... and whether the vaccine even protects against long covid in breakthrough cases I also want to see if there are any treatments for long or acute covid that...
  14. RyeRyeBread

    Covid Booster & Flu Shot Tommorrow

    I'm getting the booster and a flu shot tomorrow. I'm only 6 months into being sick (ME + POTS), and have yet to have any vaccinations - so i don't know if I'm going to have any reactions. A little concerning, but I rather not get Covid, so, we shall see. I would say I have moderate ME, though...
  15. Pyrrhus

    Reasons for no antibodies after SARS-CoV-2 Infection (Liu et al., Sept. 2021)

    Interestingly, many patients with Long Covid report that they never tested positive on any antibody tests. The following CDC study tried to determine why some people don't seem to develop antibodies after a SARS-CoV-2 infection, even though they tested positive on a PCR test. (a phenomenon...
  16. Lolinda

    Adrenal crisis caused by covid vaccine - new research

    having small issues with cortisol deficiency, I looked into research if vaccines are safe with this condition. I found these two very recent publications. I am happy that research has started on this. 5 cases who had actual or incipient adrenal crises requiring parenteral hydrocortisone ...
  17. SNT Gatchaman

    Persistent endotheliopathy in the pathogenesis of long COVID syndrome

    Authors: Fogarty et al Published: 10th Aug 2021 DOI: 10.1111/jth.15490 Full Text: J Thromb Haemostat (open access PDF) ABSTRACT ESSENTIALS Ongoing endotheliopathy is a common finding in convalescent COVID-19 patients and is independent of the acute phase response. Plasma FVIII:C levels and...
  18. Hip

    Far UVC ultraviolet light is thought safe for humans, and deactivates 99.9% of airborne coronavirus in 25 mins

    Standard germicidal UVC ultraviolet light with a wavelength of 254 nm is routinely used to disinfect hospital rooms and toilets when humans are not present, but is not safe to use when people are there, since this light has harmful effects on human skin, and is linked to skin cancer. However...
  19. Boba

    Covid 19 persistence for over a year - confirmed case in immunocompromised patient

  20. M

    Long Covid research- persistent dyspnea and exercise intolerance

    I noticed that Dr. David Systrom published a paper that resonates a lot with what I have been experiencing. Persistent Exertional Intolerance after COVID-19: Insights from Invasive Cardiopulmonary Exercise Testing. https://journal.chestnet.org/article/S0012-3692(21)03635-7/fulltext They...
  21. Phoenix Rising Team

    Rules for Posting About COVID-19 and the COVID Vaccines on PR

    Posting About COVID-19 and the COVID Vaccines To keep Phoenix Rising free of conflict and political disputes around COVID-19 and the COVID vaccines, we ask that members only post information from peer-reviewed journal articles and news sources without a strong political bias. Links and...
  22. gbells

    Post covid prion disease treatment by Jeff S DC CNIM

    Here is an interesting covid prion disease treatment. (2) Post covid prion disease treatment by Jeff S DC CNIM | Health Rising's Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia Forums
  23. H

    Do Covid Vaccines trigger reactions in MCAS patients?

    I've not had the vaccine so far as I'm worried how I'll react. And I'm completely isolated on account of my ME/CFS so I considered the risk of catching Covid much lower than having a bad reaction to the vaccine. My MCAS doctor though wants me to go for a bunch of tests and has such now wants me...
  24. frozenborderline

    Long covid, mold and mcas--Lake Tahoe 2.0?

    https://openletteropenmedicinefoundation.com/long-covid-and-environmental-toxins-lake-tahoe-2-0/ Heres a short post I made on my website about long covid and mold. Hopefully google indexes it soon. For now, hopefully I can get some eyes on it by posting it here.
  25. M

    Long Hauler trying to prepare for a 24h urine test

    Hello MCAS folks, I am a Covid Long-Hauler. For a while I have been wondering if what I am experiencing is part of MCAS, given that is the case with many other suffering post-Covid. I DO NOT have the typical symptoms like hives, swelling, low blood pressure, syncope, diarrhea. I DO have...
  26. Hip

    Survey suggests post-viral fatigue form of long COVID might be the most common subtype

    In the COVID-19 Longhauler Advocacy Project Facebook group, I posted a poll asking members of that group which subtype of long COVID they most identify with. Long COVID subtypes include: post-viral fatigue (similar or the same as ME/CFS), heart and/or lung damage (which may be permanent) and...
  27. Hipsman

    New drug that "hunts" for specific virus in cells and then destroys these cells.

    Thought this was interesting because they say it can be "tuned" to hunt for any specific virus, not just covid. Also they say it will be on the market in 2 years if everything goes to plan. This is their paper on it I think...
  28. Hipsman

    Long Covid is a missed opportunity to show that vaccines are important even for those who think that if they get covid - it will be mild.

    Title says it all. Some think that if they are healthy in their 20s, then they don’t need the vaccine, because it will be like another cold for them. Most of long haulers had mild covid, so it would be a good argument for officials to make on why it’s important to take the vaccine even for the...
  29. V

    Women and Covid vaccine

    Ths was part of a story on why women are getting more side effects than men from the vaccine. They also get Covid Arm more often (95 percent of which are from Moderna apparently) . One unexplained thing tho is why women account for 65 percent of brewkthrough infection Greater immune response...
  30. gbells

    My Concerns about the Coronavirus-19 vaccines

    I just had a discussion with my pharmacist about the coronavirus vaccines. I have concerns about the cost to benefit of the vaccines and the possibility of vaccine contamination that might injure patients. It has been discovered that asian countries have a very low covid death rate of around...