• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. Hip

    The lives of all hospitalised COVID patients given spirulina were saved; but 19% of COVID patients died in the control group not given this supplement

    An Iranian study randomly assigned hospitalised COVID patients to either receiving standard care alone, or receiving standard care along with spirulina for 6 days. The group of 91 hospitalised COVID patients who were given 15.2 grams of spirulina daily as well as standard care had no deaths...
  2. Cipher

    Impact of extended-course oral nirmatrelvir/ritonavir (Paxlovid) in established Long COVID: Case series and research considerations (Cohen et al.2023)

    Full-text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543503/ According to this table, 7 of the 13 patients in the case series experienced short-term improvements from an extended Paxlovid course, while 5 of the 13 patients experienced sustained improvements.
  3. Manuel

    Epstein–Barr virus-acquired immunodeficiency in myalgic encephalomyelitisβ€”Is it present in long COVID?

    πŸ” 𝐍𝐄𝐖 π€π‘π“πˆπ‚π‹π„ ππ”ππ‹πˆπ’π‡π„πƒ! π”π§π«πšπ―πžπ₯𝐒𝐧𝐠 𝐭𝐑𝐞 π‚π¨π§π§πžπœπ­π’π¨π§π¬ 𝐁𝐞𝐭𝐰𝐞𝐞𝐧 𝐄𝐁𝐕, 𝐋𝐨𝐧𝐠 π‚πŽπ•πˆπƒ, 𝐚𝐧𝐝 𝐌𝐲𝐚π₯𝐠𝐒𝐜 π„π§πœπžπ©π‘πšπ₯𝐨𝐦𝐲𝐞π₯𝐒𝐭𝐒𝐬 🧬 After months of meticulous review and analysis, I am proud to present a study that explores the deep connections between Epstein-Barr virus (EBV), Long COVID and Myalgic...
  4. SWAlexander

    SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

    Abstract COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear, but angiotensin converting enzyme 2 (ACE2), the receptor which binds the spike protein of SARS-CoV-2 may be important. Here...
  5. SWAlexander

    Clinical experience with the Ξ±2A-adrenoceptor agonist, guanfacine, and N-acetylcysteine for the treatment of cognitive deficits in β€œLong-COVID19”

    Highlights β€’ Combined treatment with the Ξ±2A-adrenoceptor agonist, guanfacine, and the anti-oxidant, N-acetylcysteine (NAC) reduced the cognitive deficits (β€œbrain fog”) associated with long-COVID19 in eight out of twelve patients. β€’ Two patients stopped treatment due to hypotension and/or...
  6. SWAlexander

    SARS-CoV-2 infection and persistence in the human body and brain at autopsy

    Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However...
  7. SWAlexander

    SARS-CoV-2 variants of concern emerging from chronic COVID infections, study shows

    The coronavirus variants of concern are emerging from chronic, long-term COVID infections in people who may be immune comprised and unable to clear the virus, a new study strongly suggests. Frontiers in Virology published the findings by scientists at Emory University and the University of...
  8. Pyrrhus

    SARS-CoV-2 infects, replicates, [...] and activates immune cells in human testes (Costa et al., 2022)

    SARS-CoV-2 infects, replicates, elevates angiotensin II and activates immune cells in human testes (Costa et al., 2022) (pre-print) https://doi.org/10.1101/2022.02.05.22270327 Main points: The coronavirus infects sperm stem cells in the testicles more often than previously thought. Detecting...
  9. Pyrrhus

    Persistence of SARS-CoV-2 Spike Protein in Long Covid up to 15 Months Post-Infection (Patterson et al., 2022)

    Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) up to 15 Months Post-Infection (Patterson et al., 2022) https://doi.org/10.3389/fimmu.2021.746021 A publication by Bruce Patterson and colleagues, regarding findings in the blood from Long Covid...
  10. junkcrap50

    SARS-Cov-2 Persists In Intestinal Enterocytes Up To 7 Months After Symptom Resolution

    https://www.croiconference.org/abstract/sars-cov-2-persists-in-intestinal-enterocytes-up-to-7-months-after-symptom-resolution/ Webcast of Presentation: http://www.croiwebcasts.org/p/2021croi/croi/115
  11. Hipsman

    New drug that "hunts" for specific virus in cells and then destroys these cells.

    Thought this was interesting because they say it can be "tuned" to hunt for any specific virus, not just covid. Also they say it will be on the market in 2 years if everything goes to plan. This is their paper on it I think...
  12. max_yazhbin

    Gumweed leaf tea helped me overcome Covid

    I have a pre-existing condition, multiple chemical sensitivities, which upon more recent testing looks to be caused by an insufficiency of the appropriate amino acids as well as mercury poisoning which allowed candida, SIBO, H. pylori, and ulcers to flourish. I was worried for a bit when the...
  13. nerd

    What lessons can be learned from Dr. Paul Marik regarding COVID-19?

    The COVID-19 pandemic has really shown me how the medical system works and how politics can influence the progress of a pandemic. I think there are many lessons to learn for CFS/ME. The following are some points from two webinars with Dr. Paul Marik, the leading scientists who pushed...
  14. Pyrrhus

    Long Covid: Summary of discussions

    Long Covid: A summary of discussions on Phoenix Rising So remember back in January when we were all wondering if the novel coronavirus might result in an ME/CFS-like condition? Well, I thought I would start a thread to collect together all the discussions that might be relevant to "Long...
  15. Cipher

    SARS-CoV-2's exploitation of the EMMPRIN-receptor and potential inhibitors

    It seems like the SARS-CoV-2 virus can invade host cells not only via the ACE2 receptor, but also via a receptor called CD147. [1] This receptor is also called "extracellular matrix metalloproteinase inducer" (EMMPRIN) or Basigin. [2] EMMPRIN/CD147 induces the production of matrix...
  16. Cipher

    The potential of Ambroxol in the prevention and treatment of COVID-19

    A short introduction to Ambroxol: Ambroxol is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe...