SWAlexander
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A Similar Kind of Exercise Intolerance is Found in Connective Tissue Diseases, ME/CFS and Long COVID
Results
The study found that the blood vessels of people with CTD did not dilate as much as the healthy controls. The CTD patients also displayed an “impaired stroke volume increase”. As their exercise level increased, their heart should have been pumping out ever-larger amounts of blood, but in the CTD patients, the increased blood flows ceased at an earlier timepoint.
That led to lower levels of oxygen extraction in the muscles, resulting in an early entry into the anaerobic threshold (where anaerobic energy production becomes dominant), and lower levels of energy production in the CTD patients.
Except for the reduced “systemic vascular distensibility”, which has not been measured in ME/CFS, Systrom has found the same findings in ME/CFS and long COVID.
more at: https://www.healthrising.org/blog/2...d-chronic-fatigue-connective-tissue-diseases/
Results
The study found that the blood vessels of people with CTD did not dilate as much as the healthy controls. The CTD patients also displayed an “impaired stroke volume increase”. As their exercise level increased, their heart should have been pumping out ever-larger amounts of blood, but in the CTD patients, the increased blood flows ceased at an earlier timepoint.
That led to lower levels of oxygen extraction in the muscles, resulting in an early entry into the anaerobic threshold (where anaerobic energy production becomes dominant), and lower levels of energy production in the CTD patients.
Except for the reduced “systemic vascular distensibility”, which has not been measured in ME/CFS, Systrom has found the same findings in ME/CFS and long COVID.
more at: https://www.healthrising.org/blog/2...d-chronic-fatigue-connective-tissue-diseases/