Actually, on this thread
http://forums.phoenixrising.me/index.php?threads/transdermal-b12-oils.33172/page-15#post-713827,
@Johnmac and
@Gretel seem to be taking up to 150mg of B2 a day. Currently I'm taking about 50 mg, but found that I have to keep it to morning and afternoon or it messes with my sleep. My question to them is do they adhere to Dog Person's belief that the body can't absorb more than 25mg at a time and if so, how do they time their doses?
I thought Greg, the B2 oils guy, said to take 'loads' of B2 and in order to actually replete low levels, I think other too more than 50mg/day.
Yes, I think this is exactly right. Taking supplements that put further demands on B2 and its co-enzymated form, FMN, makes it harder to replenish low stores. I did read of one scientific study where those who were on a B-Complex didn't manage to build up their stores, while those not on one did.
Who knows. I've lost track of where I saw that...