On a sidenote of possible
NADH effects:
Reference: https://sci-hub.tw/10.1139/apnm-201...d4OgcJRKSHenxJyt6DE_Cuuo2JIwoCDaC_IQ7Wg82cK8w
Immunemodulatory effects:
Reducing Oxidative Stress and MDA, increasing total Glutathione by acting on SIRT2
Might explain the big effect I have from injectible NADH as my MDA-LDL is very high, oxidative stress is VERY high, and I am having a TH1 dominance.
Just some thoughts on my personal reaction to NADH.
@mitoMAN @Learner1 (per comments on inflammation, the urine results study, dose amount, and older comments on burning)
I can pass along a tidbit from my doctors observation. Those ppl who have less inflammation do do better with NAD IV.
As to some of the thoughts in dosage... for the brain and nervous system of ppl with Parkinson's, frequency and dose that is higher do matter.
I'm not worried about these studies about urinating out nutrients. From our breathing biochemistry to our nutritional status to our glucose and other hormones, the kidneys do what they do to help. So theres more than this study's conclusions to consider.
I know when I'm crashing and my brain is having lots of problems, it's very important for me to work my way up to 1,000mg of NAD IV. That a shot or nasal spray won't help me enough.
I'm currently much stronger than I've been in 20 months. I'm very thankful and appreciative of being able to have had my months of mainly doses at 500-1,000mg of NAD.
I'm on drip now today of only 300mg though. I'm doing oxygen desat and saturation training and seeing how an IV of NAD then followed by an IV of glutathione will help me.
My work, my many hours retraining my nervous system and muscles to be stronger along with my weeks and weeks of NAD IV have shown me that the parts if tge nerve-muscle connections that currently need tge most help are the ones that appear in the brain-body map.
So if parts of the leg muscles burn, then that's where your attention will go as nutrients and hormones and just the gazillion types of biochemical reactions that are at work to help heal.
I discovered early on as we increased my dose of NAD that moving around helped. Firstly, that being hooked up to the IV actually gave me energy TO MOVE around was remarkable in and of itself. Then, movement taight me that i could help those parts i was moving or tge connective tissue patterns i was engaging to be stronger for several hours AFTER the IV.
Because i had a tremendous amount of hyper mobility and instability in my neck skull throat jaw patterns, i would also get perineural shots or later PRP shots but not deep, just Perineural style. Then those sites woukd have extra benefits of days or a week plus with PRP.
So it really depends in what you are dealing with and willing to push or explore. I started IV nutrients to get some type of stability in all those areas so that i could swallow and drink and stop gagging and have stable airway opening. Then to be able to withstand the vibration of riding as passenger in car to get IV. Then to be able to have less swallow and airway problems. Eventually I progressed to wanting energy to walk again more than to just shuffle from bed to bathroom to kitchen and such.
Now, I'm still doing IV for my brain ... but also to mount a level of healing to be free of this disease permanently.
Every increment has afforded me some bits of knowledge. This base lets me apply for myself that Options and trial and error are really important to embrace.
Tomorrow I will do only a small bag of nutrients and a 2,000 mg IV of glutathione after I do a morning session of my desaturate / then saturation oxygen training. My doctor and i will explore 2 consecutive days of IV glutathione (small bag of nutrients before) as per what was shared in the video on YouTube of another doctor sharing about great benefits of O2 and IV glutathione.
That video is one I shared in my post about oxygen earlier. I'm more than ten years in this disease and really really am ready to live well and vibrantly without it ever again.
I've far exceeded what results I wanted to get in the beginning from IV therapy. What i have learned this past 20 months from reading about other's stories is that it is at the 6 month mark where improvements that last are to be had. I've often stopped at 2 months or at 3 months. Now, for the next 3 years, I'll be pursuing getting rid of this disease forever for myself.
And there are many days when I don't want to push myself to do the program I've set up. Like this morning, I did not want to get out of my warm bed to go turn on the oxygen concentrator. But it is the thing now that let's me walk without discernible calculation that I am even using energy. That is a huge benchmark of improvement from having a spoon debt to counting and debating how spoons will be used to not even recognizing that spoons or energy of any kind is being utilized.