Cyclosporine - the Good, the Bad, & the Ugly

Cyclosporine is a mycotoxin. Mycotoxins are harmful products produced by fungi. They are chemical in nature and are immune suppressing. Fungi rely on the mycotoxins they produce to kill any bacteria, other fungi, viruses and anything else that might compete with them. They suppress the immune system in dogs, cats, & humans.

the Good - The immunosuppressive effects of cyclosporine were discovered in Switzerland in 1972 and it was used successfully in preventing organ rejection in kidney transplants. Apart from transplant medicine, cyclosporine is used for a variety of skin conditions in both humans and pets. Of course, in transplant patients it suppresses the immune system so they do not reject transplants . Atopica (cyclosporine) touts it's efficaciousness with dogs who have allergies and other dermatological conditions .

the Bad - The side effects of this drug include - headaches, nausea, vomiting, shaking hands, swollen bleeding gums, cancer, kidney failure, hypertension, easy bruising, hearing problems, yellowing of skin and eyes, loss of consciousness, vision changes, swollen glands, immune suppression and dizziness .

the Ugly - The FDA ( Food & Drug Administration) has 17 pages of adverse events that have been reported for oral use of Atopica (cyclosporine) in dogs. The fifth adverse event is pruritus (itching ).
Nurses have strict rules and protective actions to take when administering cyclosporine (the active ingredient in Atopica )
Farmers are familiar with the deleterious effects that mycotoxins can have on animals that eat moldy grain containing mycotoxins .
Some examples of mycotoxins found in nature are Aflotoxins, the most potent carcinogen on earth and ochratoxins - both produced by an Aspergillus fungi .
Cyclosporine is used in skin ointments and even eye drops .

Information from author:
Dr. Deva Khalsa - veterinarian
Likes: Paralee


Ugh! Thank you. Maybe that's why my dog chews himself up with skin problems, not to mention us humans and our problems.

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