Vascular Compression: Summary of Discussions

[Pyrrhus]

I thought I'd start a thread to summarize the discussions about vascular compression and any possible relation to impaired collagen.

Here's an interesting comment from another thread:

This may be totally out of the box, but has anyone considered vascular compression syndromes to be a part of this? I am finding that they are pretty rare (or severely misdiagnosed) and many doctors don't know a lot about them. Many with hEDS have Median Arcuate Ligament Syndrome (MALS), Nutcracker, Mals Thurner, etc. These are vascular compressions that affect blood flow to the organs, the heart, etc. Most patients with compressions have horrible fatigue. Those with connective tissue disorders can be born with their diaphragm lower than normal and this can lead to vascular compression problems as organs sort of float, droop lower. This drooping can cause artery and vein compressions, reducing blood flow often drastically. Compression disorders also compress and affect the nerves that go through the celiac plexus and other nerve bundles, including the vagus nerve. Compressions cause not only GI symptoms but also dysautonomia, POTS, chronic fatigue, severe pain, etc.

 

[Pyrrhus]

Related discussions:

A Tough Nut to Crack: Chronic Fatigue Syndrome and Abdominal Pain Attributed to Nutcracker Syndrome (2017)
https://forums.phoenixrising.me/thr...attributed-to-nutcracker-syndrome-2017.78333/

Understanding jugular venous outflow disturbance
https://forums.phoenixrising.me/threads/understanding-jugular-venous-outflow-disturbance.78549/

POTS and MALS (abdominal vascular compression)
https://forums.phoenixrising.me/threads/pots-and-mals-abdominal-vascular-compression.52518/

Thoracic Outlet Syndrome - just diagnosed
https://forums.phoenixrising.me/threads/thoracic-outlet-syndrome-just-diagnosed.49583/

Are connective tissue problems related to dysautonomic mast cell activation?
https://forums.phoenixrising.me/threads/what-exactly-is-dysautonomia.86647/#post-2396128

 

[Pyrrhus]

Interesting comment from another thread:

There has been a couple of studies done that looked specifically at the celiac artery velocity of groups of POTS patients in general, and interestingly, in excess of 50% of the POTS patients (and as much as 73% in one study) had velocities that would qualify them for having Median Arcuate Ligament Syndrome (MALS - a.k.a. celiac artery compression syndrome - a celiac artery doppler ultrasound PSV exceeding 200 cm/s at end of full expiration, as done for assessing MALS).
I say they "could qualify for having MALS" as a mesenteric CTA doesn't back up the finding of an elevated celiac artery velocity in a significant percentage of cases (about 30%) and this is where it is hypothesised to be called 'neurogenic MALS'.
https://www.autonomicneuroscience.com/article/S1566-0702(15)00289-1/fulltext#relatedArticles

 

[junkcrap50]

Doing Gods work @Pyrrhus adding so much data and knowledge and linking discussions together. Not just this thread but many others. Very important to help make PR a repository of information.

 

[Pyrrhus]

Doing Gods work @Pyrrhus adding so much data and knowledge and linking discussions together.

Thanks so much!

But it really takes a community to make Phoenix Rising what it is, so everyone is welcome to start linking related discussions together and sharing any news and research that they come across!

 

[junkcrap50]

Thanks so much!

But it really takes a community to make Phoenix Rising what it is, so everyone is welcome to start linking related discussions together and sharing any news and research that they come across!

Just wanted to let you know it’s appreciated and it’s going unnoticed! I try when I can but you’re encyclopedic in your documenting!

 

[Boba]

Court’s latest piece on this topic:

https://www.healthrising.org/blog/2...5OIzj2SoqBzogpkI2sIzOA05VdCskr2CMROb6ugTucUAY

 

[SWAlexander]

Dr. Scheibenbogen speaks also of vasoconstriction (insufficient oxidant toward energy in muscles).
https://www.sciencedirect.com/science/article/pii/S0889159115300209

 

[ChookityPop]

Is it possible to identify vascular compression syndromes through whole genome sequencing?

 

[Rufous McKinney]

personally, I think its possible we experience an induced hEDS state via the collagen damage being elicited by the viruses lurking long term.

In addition to organs being not QUITE in their correct locations, imagine ducts and glands and organs which must secrete something. Losing some of their 3D physical structure. From collagen breaking down.

 

[ChookityPop]

personally, I think its possible we experience an induced hEDS state via the collagen damage being elicited by the viruses lurking long term.

In addition to organs being not QUITE in their correct locations, imagine ducts and glands and organs which must secrete something. Losing some of their 3D physical structure. From collagen breaking down.

Why would the organs not be in the right place? I talked to a severe ME patient Who said he had organs moving around and not being in the right place, Vascular Compression he had surgery as there was something pressing on vessels and the surgery alleviated the POTS somewhat But I dont know to which degree. Connective tissue disease, autoimmunity and viruses etc.

 

[Rufous McKinney]

Why would the organs not be in the right place?

well ligaments and fascia support organs and hold them on various locations and the first post reported dropping of organs. collagen a major component of those tissues.