The Resistant Starch Challenge: Is It The Key We've Been Looking For?
- Thread starter Ripley
- Start date
I'm a FUT2 non-secretor (rs601338 AA) and trying to understand the fucosylation stuff. I had no growth of bifidobacterium on a CDSA last year, I have CFS and initially felt much better on amoxicillin, but declined considerably after it damaged my gut.
Are we sure that being a non-secretor means that we want to supplement directly with fucose-containing foods? Do bifidobacterium consume the fucose in the food or the fucosylated compound (which it seems I cannot make)? My knowledge of biochemistry is amateur at best, so this might be a dumb question.
Not sure I'll be able to find a wet nurse...
Are we sure that being a non-secretor means that we want to supplement directly with fucose-containing foods? Do bifidobacterium consume the fucose in the food or the fucosylated compound (which it seems I cannot make)? My knowledge of biochemistry is amateur at best, so this might be a dumb question.
Not sure I'll be able to find a wet nurse...
Thanks @Ripley, I'm interested to hear more.
I came across this while I was researching- not sure if it relates, but it gave me pause:
http://www.ncbi.nlm.nih.gov/pubmed/17697405
But I think free fucose is what the bifidobacterium produce? Rather than pre-fucosylation?
I came across this while I was researching- not sure if it relates, but it gave me pause:
http://www.ncbi.nlm.nih.gov/pubmed/17697405
But I think free fucose is what the bifidobacterium produce? Rather than pre-fucosylation?
YouTube video not for the squeamish. (UK viewers may know what it's about if I say "Little Britain bitty")
BTW the breast is probably a prosthetic - they use a lot of prosthetics in the series.
Sorry but I couldn't resist.
BTW the breast is probably a prosthetic - they use a lot of prosthetics in the series.
Sorry but I couldn't resist.
In lieu of a wet nurse, perhaps it would be good to start taking L. Reuteri -- what is found in breast milk.
http://www.iherb.com/Nature-s-Way-P...isc=0&lc=en-US&w=l reuteri&rc=13&sr=null&ic=1
http://www.iherb.com/Nature-s-Way-P...isc=0&lc=en-US&w=l reuteri&rc=13&sr=null&ic=1
Coffeeberry is apparently a source of mannose, galactose, fucose, xylose, arabinose and glucose. Besides this, it's a very powerful antioxidant. This sounds like a great combo, as the antioxidants can counter the oxidative stress from the immune activation.
I might try this, and combine it with shark cartilage. As I already take egg white protein, the combination of coffeeberry and shark cartilage should get me covered in all the glyconutrients.
I might try this, and combine it with shark cartilage. As I already take egg white protein, the combination of coffeeberry and shark cartilage should get me covered in all the glyconutrients.
Just need to check something. Can someone quickly tell me if these foods are of any help/relieve with the symptoms/way to recovery?
Truth is, we aren't so much after fucose per se as we are fucosylated glycans (i.e. proteins, lipids with fucose molecules). Bacteria metabolize glycans (virtually all prebiotics are glycans), which is helpful because the glycosidic bonds that link these sugars to various molecules are indigestible to us (as they should be if we want our flora to access them).
So, bacteria forage on these glycans and they metabolize them into various things for us. And that way the gut bugs can help us both to exploit fucosylated glycans from plants and add it to the mucosa. It needs the adult flora to do that.
Just having fucose in the gut doesn't necessarily mean it will get added to the gut mucosa.
- sprouted legumes with the roots
- Licorice
- or in fact any of many other legumes:http://en.wikipedia.org/wiki/Legume
- okra
- black currant
- bee honey, bee venom
- Lotus, lotus seeds
- sunflower
- Licorice
- or in fact any of many other legumes:http://en.wikipedia.org/wiki/Legume
- okra
- black currant
- bee honey, bee venom
- Lotus, lotus seeds
- sunflower
Truth is, we aren't so much after fucose per se as we are fucosylated glycans (i.e. proteins, lipids with fucose molecules). Bacteria metabolize glycans (virtually all prebiotics are glycans), which is helpful because the glycosidic bonds that link these sugars to various molecules are indigestible to us (as they should be if we want our flora to access them).
So, bacteria forage on these glycans and they metabolize them into various things for us. And that way the gut bugs can help us both to exploit fucosylated glycans from plants and add it to the mucosa. It needs the adult flora to do that.
Just having fucose in the gut doesn't necessarily mean it will get added to the gut mucosa.
Thanks for checking into this @Ripley !
Licorice root extract is a component of Equilibrant, which helps a subset of people with CFS. Though, it has many functions, so hard to say whether the glycans are the part that helps.
Licorice root extract is a component of Equilibrant, which helps a subset of people with CFS. Though, it has many functions, so hard to say whether the glycans are the part that helps.
@Ripley, I just had a great idea (!)((mediocre ideas come left and right, but this may be my first great one, ever)).
And the simplest thought spurred the whole thing; I wish all this thread information was condensed, perhaps simplified somewhat, and mostly about steps to take and things to do with minimal (sure, some would be fine) emphasis on the underlying reasoning (not at all to disparage, just the opposite, but there's just a certain number of Vegas(s) out there, as in not many).
Actually, (hope not) this may encourage breaking some forum rule or other so I'm forced to use an extremely complex code you must decipher to consider this grand scheme. Uh, okay, there's things you'd need: like a name (catchy would help); a lot of time on your hands; a really good mind (you got that); a front cover and --this code business is tricky-- you know, one in back, too; things like that.
Know what, if this is too indistinct just pm me, I'll spell the whole thing out. Good luck, hope you'll think it over.
And the simplest thought spurred the whole thing; I wish all this thread information was condensed, perhaps simplified somewhat, and mostly about steps to take and things to do with minimal (sure, some would be fine) emphasis on the underlying reasoning (not at all to disparage, just the opposite, but there's just a certain number of Vegas(s) out there, as in not many).
Actually, (hope not) this may encourage breaking some forum rule or other so I'm forced to use an extremely complex code you must decipher to consider this grand scheme. Uh, okay, there's things you'd need: like a name (catchy would help); a lot of time on your hands; a really good mind (you got that); a front cover and --this code business is tricky-- you know, one in back, too; things like that.
Know what, if this is too indistinct just pm me, I'll spell the whole thing out. Good luck, hope you'll think it over.
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Ha, ha, so get Sushi to read it, we don't have too many Navajo speakers here in Virginia. It's actually encoded in ROT13.
On a serious note, do you get any myoclonus symptoms? The obnoxious jerky, twitchy muscle stuff. I don't recall.
On a serious note, do you get any myoclonus symptoms? The obnoxious jerky, twitchy muscle stuff. I don't recall.
Good try, but aren't we forgetting it needs a degree of difficulty in deciphering? Hmm?
Can you send me some?
Don't be disgusting!