I'm still waiting for Novavax. I'm worried about the effects on the innate immune system. Novavax doesn't have this problem. It should just trigger adaptive immunity and not the whole chain of the immune system that might participate in ME pathophysiology. The only thing that might cause issues is the immunity enhancing adjuvant. But I expect it to be safer because it's limited to the muscle, unlike the mRNA from mRNA viruses.
I had been waiting on Novavax too. But why would It not affect the innate immune system? Agree it’s likely safer than the mRNA. But ever since some research showed the spike protein itself by itself can be pathogenic Novavax would have that risk. But you’d receive a small fixed dose of it.
He did not give me a prophylatic ivermectin RX- which I suspect does not exist. Ivermectin is taken short term.
Some interesting studies on Ivermectin prophylactic 1x/week ivermectin in Indian healthcare workers treating COVID patients showed effectiveness.
What does everyone think about constant vaccines causing ADE?
Strong possibility. Any time you have a leaky vaccine, it’s possible. Plus COVID is a respiratory virus which mutates very quickly, increasing the opportunities to cause ADE. Plus history of terrible ADE in previous SARS coronavirus vaccines. So, can’t discount it. But if it happens, there’d be no consensus if it’s happening, so I worry ADE would advance to serious instead of catching it when it’s mild.
Actually they are projecting that it's less immunity from getting COVID rather than the vaccine not more.
I’m sorry but that just isn’t true - or at least is not the current thinking. It may have thought to be true/flip flopped early on or at one point. Natural immunity appears to be longer lasting as the experts are admitting now vaccines are temporary ~6mo and need booster shots.
It seems like all of the vaccines for covid contain some sort of novel technology. The novavax would be the closest to something 'old school', but even that is using a new adjuvant from plant saponins.
Even more traditional/old school than Novavax is the French vaccine Valneva using inactivated whole virus, who just expanded their phase 3 trials. And the press says it can offer protection against variants. Though I don’t know how it’s different or why it’s more effective than the Chinese or Indian vaccines. It looks like it will get approval in UK at the end of the year.
There's no reason for others who have had the vaccine to fear being around the unvaccinated, since they're protected.
That’s how it should be, but it’s not. But fear what? Catching Covid: No, vaxxed people can still get it. The thinking has changed. Fear hospitalization & serious illness: yeah probably true, though if you have multiple risk factors like obesity, age, heart disease/hypertension, diabetes, etc hospitalization/serious is still possible. Fear is personal risk tolerance + probability %s, which is why there is so much polarization.
Severe cases are just a subset that depends on viral load.
That‘s the current thinking. But I just hear da day or two ago about a study showing viral load != severity. What subset? I assume you mean risk factors (age, obesity, cardio, etc.)
Edit: My striked out comment is very likely not true. Edited so I didn't want to spread fake news. I was just repeating the headline I heard without looking into it; mistake to do that. The study was weak/not well designed and anyway there are far more studies showing the opposite: viral load influences severity.
he had some bad news about herd immunity. It's not going to happen. Because the jabs are not effective enough and getting infected does not provide long lasting protection. So covid will still have people to infect. It wont go away.
Yes. This is probably true and likely was always going to be this way. But this is the nature of respiratory viruses. They mutate and spread so quickly that you heard immunity is harder to reach.
However, over time, the risk of & disease severity will decrease significantly - hopefully and likely to regular everyday colds and flus. (This has happened with other pandemics: Spanish flu, 1960s Asian flu - we have both today & very mild) This is bc natural mutation selection skew towards milderness illness (yes still possible for mutation that is nughtmareish). And bc frequent exposure to normal viruses and colds will build, strengthen, & boost natural immunity. History of normal choronovirua colds do provide some limited cross protection to Covid virus. And Getting COVID 1,2,3 times (on population scale) will add more and more epitopes for immunity. So any new mutations are lower severity from partial immunity and weaker mutations.
The worrying part that could be possible is due to lockdowns and masks, every day colds, flues, etc are not being encounters and not provided mini immune boosters. This is starting to be seen in RVS in children now, some think.
Therapeutics would be a way to get to this new equilibrium faster.
I just heard from a friend in Texas. At the beginning of this week she had 5 people in her friendship circle in the hospital with Covid. Two are now dead. A third is expected to die anytime and the other to are on ventilators.
None were vaccinated. She is bereft.
Bill
That’s terrible. Sorry to hear that. Shame when I agree could have been prevented. Did they have any risk factors (obesity, age, high bp or cholesterol, cardio disease, diabetes, low vit D, etc.) 3/5 dead, even with such a small sample, seems likely to happen in healthy adults just based on %s.
Blame is well-placed when it comes to those who spread misinformation, who increase vaccine hesitancy, and who risk their lives and the lives of others by not masking and not vaxxing w/o cause. 100%. Those people are blameworthy.
Ivermectin is not effective for Covid. That has been demonstrated by results of a study released just this week. HCQ does not work either,suggesting otherwise is just not so.
Polarization is due to facts and truths being impossible to agree upon. Due to several things: seeing two different movies on the same screen (2 people see what each other sees yet will say the opposite of what just happened even if it’s not interpretable); interpretable data; confusing and contradictory statements; lack of consistency from & trust of credible figures; widely different data & #s for various subgroups; not ident offing subgroups when discussing facts; widely different risk profiles regarding the virus itself, therapeutics and drugs, and vaccines and on several levels: personal level, community, and policy level; overflow of huge amounts of rapidly new changing data and information not possible for all to keep up; miscommunication from not specifying exact narrow boundary conditions of topic of discussion; varying acceptance and rejection of sources; personal experience/annectdotes influencing facts/data/opinions; and arrrogance/lack of humility/strongly held beliefs when discussing “facts” or “truths” each know thinking they known best and are right-other wrong.
For example, many would strongly disagree regarding ivermectin and hydroxychloroquine.
So it’s hard and misdirected to place blame in any direction. Especially when you have such a diverse and widely different (on tons of levels) population to manage, who share different priorities, trust, and group references. Perfect or even successful handling of Covid was never ever going to happen.