Bret Weinstein is quite intelligent and has some very valid criticisms of much of the mainstream research. Unfortunately, his incisive criticism loses that edge when pointed at his own ideas. Like many in the mainstream, he's not consistent in the rigor of his criticism or data. For instance, some of Bret and Heather's extreme anti-mask criticism is based on their 'feelings' seeing kids and vague thoughts of devastating 'evolutionary' effects of masking (even though there are many cultures where masking is not new and they are basing this on PhD feelings, not published research or even well formed hypotheses).
In short, I like to hear his opinion and like that he has his own views. I think his ostracism and censorship is unfair and a sign of the rot in our systems.
I think his criticism of the 'certainty' of mainstream medicine when the data is not supportive is very fair. I think his touting of his own certainty (on Ivermectin, the dangers of mRNA, who really invented mRNA vaccines, masks are destroying children's emotional development) could use some of the trademark Weinstein skepticism.
Ivermectin, for instance, is not new to the ME/CFS community. Some have had decent results, some have not. It seems relatively safe, but no one seems to know why people without positive parasite tests seem to benefit, and others with the same symptoms don't. So we are familiar with that uncertainty, and my first spider tingle that something is amiss is when I hear certainty in others when it shouldn't be there.