Is your Hypothalamus up the creek?

Wishful

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I just came across this paper ( https://www.frontiersin.org/articles/10.3389/fnins.2020.536682/full ) which is about the complexity of astrocyte metabolism, which in turn affects brain metabolism. There are all sorts of metabolic processes going on in those cells, affecting other brain cells, so even a minor dysfunction there could result in disruptions in other brain functions. The effects can be regional, which could explain why ME varies so much. This fits into this thread, since astrocytes control the hypothalamus too.
 
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I definitely think it plays a role. I had hypothalamic amenorrhea and a variety of hormonal imbalances for several years before diagnosis. I don't think its the cause per se, but I think its an important part of why I was susceptible in the first place. I've also experienced treatment-resistant depression and childhood adversity, which have been proven to cause changes in volume in the hippocampus.
 

andyguitar

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Screenshot 2024-12-02 at 22-27-31 Hypothalamic deep brain stimulation augments walking after s...png

Scientists have discovered that the Hypothalamus has a role in movement. Cant help wondering if this might explain why some with me/cfs sometimes are unable to move/feel their legs if the Hypothalamus is up the creek.
 
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