Completely eliminated my severe anxiety symptoms with three supplements!

mariovitali

Senior Member
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1,216
@mariovitali What brand of TUDCA are you taking? I tried two different ones with little to no response.

It is from Premium Powders, although i believe that TUDCA on its own will not help. The whole regimen is about making sure that ER Stress does not take place and there are many ways to do this (which are discussed in my post).
 
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@Kenshin
You might also want to Google search about the psychedelic herb Iboga for PTSD treatment. There are some good anecdotal reports. Note that you do not need to go through the full psychedelic trip on Iboga to get its treatment benefits (and this would not be recommend at all for ME/CFS patients): many have found that microdosing Iboga works just as well. I tried Iboga microdoses (taking around 50 mg to 150 mg sublingually each day), not for anxiety but for some other mental symptoms I am trying to fix (namely anhedonia and blunted affect). It helped a bit, I think.

Hip,

I have considered Iboga treatment (as well as ayuhuasca) for several reasons. But it is not a very accessible treatment. I am curious....how did you get it?
 
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You know something? I think this NAG, flaxseed and curcumin is actually working! I have quite severe anxiety, PTSD, major depression and fibromyalgia and since taking this in the past few days, I feel like I have been taking some kind of balm of contentment - finally, after trying so many things, the bottles of this and that have runneth over my house. Thank you so much!!
 

Hip

Senior Member
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18,148
@BarbCat
Please to hear that this anti-anxiety treatment is working for you. I am continually surprised at how these three supplements seem to benefit many people. Of course they do not work for everyone, but when they do work, they seem to be pretty effective.

And if those three do not fully eliminate your anxiety, you can further increase the anti-anxiety effect by adding on a few more supplements from my list given in this post. Good additional anti-anxiety supplements include vinpocetine, high dose vitamin A, transdermal magnesium cream.

If like me you have intestinal conditions like irritable bowel syndrome, then inflammation from this might be contributing to your anxiety, and I found that prebiotics, probiotics, and particularly the yeast probiotic Saccharomyces boulardii, further helps reduce or eliminate anxiety.

Is your anxiety of the generalized anxiety disorder (GAD) type, by the way?


Note that the three main supplements are NAG, flaxseed oil and turmeric, rather than curcumin. Turmeric contains curcumin, but also contains many other compounds.
 
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Thanks, Hip. It hasn't completely eliminated my anxiety which every now and then washes over me like a black wave, but I've been using curcurmin and am right now ordering turmeric from Amazon. I don't really know what I have, it's been called bipolar depression but I don't think so. Have had long, long episodes of ceaseless panic attacks and definitely PTSD. Had a pretty traumatic childhood and traumas don't end just because you leave home. My husband and I just recently had 4 years of unbelievable shit hitting the fan, over and over and we're still recovering from it.

It's been purported by an epigenetic physician that my symptoms (and my father's and grandmother's) sound like toxic copper overload, and my symptoms sure match it. Waiting for the test results to come in to verify it but I'm not convinced there's a whole lot to do about it. His is nutrient therapy so I'll just have to wait and see, but in the meantime, hope your trio helps and I'm wondering if it's something that takes some time to really kick in. It's not always terribly bad, but I just have to hang on and white knuckle it when the attacks hit, but thank God, they're lessesning. Looking forward to reading your previous post of why this stuff works and thanks for all your good work.
 

Hip

Senior Member
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18,148
In case it is of any use to you, there is a fairly comprehensive list of different classes of drugs with anti-anxiety effects given in this post.

I have also read some interesting articles about psilocybin mushrooms (magic mushrooms) being a treatment for PTSD.

MDMA (ecstasy) also seems to help PTSD. MAPS have done some interesting work on MDMA-assisted psychotherapy for PTSD.


Note that panic attacks / panic disorder is a different category of anxiety disorder than generalized anxiety disorder (GAD). I have GAD, and I think the supplements on this thread work for those with GAD. I am not sure if these supplement can also help panic disorder, though it is worth trying. Panic attacks usually are short duration events of one or two hours maximum.
 
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Hello,

Can anyone confirm the following:

(a) Should flaxseed oil and turmeric powder be taken before or after food (empty stomach or otherwise) and can both be taken together or should there be a break in between?

(b) Can flaxseed oil be taken in capsule (soft gel) form since it's more readily available. I'm thinking 4000mg flaxseed oil a day. Will this be as effective as 1 tbsp of the oil?

I'd like to add NAG to this regimen but I'm unable to find it in my country.

Thanks in advance for your help.
 

Hip

Senior Member
Messages
18,148
Hi @Indus
Flaxseed oil is best absorbed with food. Turmeric may be better on an empty stomach (unless this causes irritation, in which case take with food). NAG should be on an empty stomach. (I have now updated the first post in this thread to include this information).

You can take flaxseed oil as capsules, but it will be expensive, because the daily dose necessary to achieve an anti-anxiety effect is 15 ml of flaxseed, which is around 13000 mg in weight.

I sometimes buy NAG from iHerb.com in the US, who are very cheap, and it takes only around 3 days to arrive in the UK. And Health Monthly in the UK has good prices, and also ship internationally at low costs.
 
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Thanks @Hip, good to know.

I just wanted to clarify a few more things, if you don't mind.

Is it effective if you take Turmeric on its own or should it be combined with Piperine for better absorption? I've read that turmeric absorbs poorly in the GI tract unless combined with piperine.

Secondly, have you tried (or have any views about the use of) Bovine Colostrum powder for anxiety? It is nature's "first food" and is famed for its anti-inflammatory and anti-fatigue properties. Its effect on IBS and gut healing is also well documented. I've been experimenting with 2400 mg of bovine colostrum for a few days now and have noticed some "healing" effects including a slight alleviation in mood.

At this point, my primary concern is getting rid of debilitating lifelong anxiety (specifically those horrible, recurring episodes of "anticipatory anxiety" and fight-or-flight responses before important events). If I can subdue that demon then my life would be so much better and balanced :balanced:
 

Hip

Senior Member
Messages
18,148
Is it effective if you take Turmeric on its own or should it be combined with Piperine for better absorption? I've read that turmeric absorbs poorly in the GI tract unless combined with piperine.

Piperine I know helps curcumin absorption, but my guess is that one or more of the other components of turmeric are responsible for most of the anti-anxiety effect. Whether piperine helps in their absorption, I don't know.



Secondly, have you tried (or have any views about the use of) Bovine Colostrum powder for anxiety?

Good doses of colostrum (two or three heaped teaspoons of powder) I found helped my anhedonia symptoms a little, but in my case I did not notice any anti-anxiety effects.



At this point, my primary concern is getting rid of debilitating lifelong anxiety (specifically those horrible, recurring episodes of "anticipatory anxiety" and fight-or-flight responses before important events).

Anticipatory anxiety I think is more connected to panic disorder (PD), rather than generalized anxiety disorder (GAD). I had GAD, and these supplements often seem to work well for those with GAD, judging by the feedback on this thread. Whether they might be helpful in the case of PD and anticipatory anxiety, I do not know, because not many people with PD have tried the supplements and given me feedback.

Adrenaline and noradrenaline underpin the body's fight-or-flight response, and beta blocker drugs like propranolol suppress their release, thus calming an over-active fight-or-flight response. Have you asked your doctor about trying beta blockers?

SSRI drugs are also good treatments for PD. I know it is nicer to treat symptoms with supplements if possible, but it may be a good idea to explore drug options too. I had severe mental side effects from SSRIs, so could no use them. Lexapro (escitalopram) is well known for being one of the most well tolerated SSRIs.
 

trails

Senior Member
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114
Location
New Hampshire
@Hip, do you think there is any advantage to splitting the flaxseed dosage in thirds (with breakfast, lunch, and dinner) or do you think it would be better to take the complete dosage once a day? Just curious...thank you!
 

Hip

Senior Member
Messages
18,148
@Hip, do you think there is any advantage to splitting the flaxseed dosage in thirds (with breakfast, lunch, and dinner) or do you think it would be better to take the complete dosage once a day? Just curious...thank you!

My guess is that it is the alpha linolenic acid in flaxseed oil that has the anti-anxiety effects. I don't know the elimination half live of this, but if it were short, then multiple daily doses might be better, and if it were long, then a once daily dose would be fine. My impression is that the anti-anxiety effects of a once daily dose last for the whole day.

The main issue with flaxseed oil is the diarrhea that occurs once you go above around 20 ml daily (that was the threshold for me anyway). This limits your maximum daily dose.
 

MeSci

ME/CFS since 1995; activity level 6?
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Cornwall, UK
My guess is that it is the alpha linolenic acid in flaxseed oil that has the anti-anxiety effects. I don't know the elimination half live of this, but if it were short, then multiple daily doses might be better, and if it were long, then a once daily dose would be fine. My impression is that the anti-anxiety effects of a once daily dose last for the whole day.

The main issue with flaxseed oil is the diarrhea that occurs once you go above around 20 ml daily (that was the threshold for me anyway). This limits your maximum daily dose.

I looked in a lot of detail at alpha-linoleic acid some years ago, specifically about conversion to EPA and DHA, and found that there is a lot of variation between people with regard to how they handle ALA (sometimes called ALNA - ALA is also used to refer to alpha lipoic acid).

It depends on age, gender, health status, diet, etc.

This paper discusses conversion between fatty acids in vegetarians, for example.
 

juniemarie

Senior Member
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@MeSc Thank you for posting the link to that article. As a vegetarian I am often perplexed about what I need to do to supplement fatty acids that one would normally get in meat.
The conversion of fatty acids to the various forms. ALA to EPA & DHA has always been beyond my ability to understand, as is the balance/ratio between 3 & 6 fatty acids.

I am printing the article out and hope going over it in small increments over time will help me understand.

If one of you more scientific thinkers can add any info to facilitate my process, in laymen's terms, it would be greatly appreciated;)
 

MeSci

ME/CFS since 1995; activity level 6?
Messages
8,232
Location
Cornwall, UK
@MeSc Thank you for posting the link to that article. As a vegetarian I am often perplexed about what I need to do to supplement fatty acids that one would normally get in meat.
The conversion of fatty acids to the various forms. ALA to EPA & DHA has always been beyond my ability to understand, as is the balance/ratio between 3 & 6 fatty acids.

I am printing the article out and hope going over it in small increments over time will help me understand.

If one of you more scientific thinkers can add any info to facilitate my process, in laymen's terms, it would be greatly appreciated;)

You should be able to get vegan/veggie EPA/DHA supplements. I do. I think it would be difficult to figure out whether you are a 'good converter' or not.
 
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Hi,

I am so glad I came across this page. I have a quick question. I took 1000mg of turmeric this morning and second dose of 1000mg around 3pm. Half hour or so after taking the second dose I felt very "different". My mood changed to more chillaxed and pleasant but kind of nervous and shaky at the same time. I have a pretty sensitive body and react more to everything than average person does. I have read online some people take over 10,000mg daily so it might all depend on an individual.

Do you think I should limit turmeric intake to just 1000mg(500*2) a day? Also do you reccomend the one with higher availability or just normal one? I took normal one today for the first time.

I have not bought other 2 supplements yet.

Thanks
BIONN
 

Hip

Senior Member
Messages
18,148
@BIONN
Large doses of turmeric can cause diarrhea. There may be other problems with high doses, which I am sure Dr Google will tell you about. Check for liver issues. But you could certainly try say 2000 mg twice daily. I have not tried higher bioavailability turmeric. I buy 1 kg of turmeric powder sold for cooking for around £3 ($5).
 
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