Hi Fredd ! Love your work.
I had liver pain, very low ceruloplasmin and serum copper and very low manganese, and liver pain, and issue with very low potassium. I saw your post so i took lithium orotate 5mg and it was awesome my potassium deficiency was less high and my liver pain was much much better, but the issue is it seem like the orotate give me very high ammonia. So i want to continue taking lithium but in what form do you think i can take it instead of orotate ? It seem like ionic liquid lithium chloride is the only option for me.
And do you know if boron is too needed for potassium balance ?
Best regards,
Nicolas
Hi Nicolas,
Things are not optimized. I have a method I have worked out how to get pretty good results for many people. The logic of this works this way. Initially One takes all the micro-nutrients. vitamins, B-complex like B-Right to get healing started With low quantities of Lithium in the form of Transcobalamin Receptor L,i the progressions with epithelial tissues is where things tend to start obvious healing. Then after all the basics are started one starts with MeCbl of the deadlock quartet. After that gets things going, keep thing going until a set of symptoms gets worse. Those will be things like methylfolate and/or potassium, often alternating This key into the Refeeding syndrome list of nutrients. It isn't complete. People differentiate into different sequences and combinations.
Boron is essential. A lack of sufficient boron and it can feel fatiguing and causes bacterial films like on teeth and uncontrollable tooth decay. At the same time one might have dark gums and deterioration of gum tissue and lose ones teeth from low copper (can be in mid range, but that is because it is not being used). My liver problems cleared up when I could get copper to above mid range with the help of TCR-Li. As far as my hypothesis is that the liver grows TCR-Li and the cells to generate copper enzymes. I had to take low amounts of iron for a while. Copper also reduced MCV from above 100 to below 93 after getting enough MeCbl and 45 mg of methylfolate. It wasn't mater of jumping from 1000 mcg of mfolate to 45,000 mcg. Instead I found that the bottlenecks had to be built. Increasing doses by 1 mg a day with seems to work in build supply lines.
All of the micronutrient minerals can cause serious problems if bottle-necked or deficient.
The order is important as the nutrient order is in order of bottlenecks in making cells. The only symptoms getting worse are the ones to increase the nutrient. Those symptoms respond in hours telling you it is the correct nutrient to add.
Different people may have different orders of deficiencies and bottlenecks. Several people had sudden bottlenecks for type of methylfolate and they had to switch to Quatrefolic from Metafolin for a few days and switching back worked. Also several of us have had to switch from L-carnitine tartrate or ALCAR or LC fumarate and so on. I had to try multiple different copper formulations until I found one that I could tolerate and work. As some things healed, some things stopped working or switched to a different pathway.
TCR-Li needs cob[ii] to make more cob[ii], the active catalyst form of B12. In the beginning nobody has much any more. It takes the deadlock quartet (MeCbl, AdoCbl, L-methylfolate and L-carnitine (fumarate or other) to grow cells with TCR-Li. First up is oral mucosa with TCR-Li. Then after those are built, the liver and kidney TCR-Li is built. I had two years of increased liver healing from 1+ to 3+ years and kidney healing with functioning TCR-Li that now retains B12 for up to 18 hours instead of excreting it in 1-2 hours in urine.
It always puzzled me that b12 being " water soluble" would pour multi mg of B12 out the kidneys while the gut had a massively complex B12 system for absorption that fought hard and expensively to preserver 2 mcg of B12 in the body. That seems to be a non functional logic. It doesn't make sense that the B12 for the CNS/CSF would be thrown out en mass whereas minute amounts are struggled to hold onto expensively for the body. and the CNS/CSF is starved of B12. Now instead the TCR-Li in mouth can absorb large amounts of B12 from meat and MeCbl and AdoCbl sublingual and retain the bulk of the B12 for much of a day as it gets distributed in the CNS/CSF instead of being exceed within 1-2 hours mostly. And along with these things it appears to take some years to grow enough TCR-Li to balance all sorts of nutrients like electrolytes and regulates healing.
