Hi Fredd,
Thanks for all the information you have shared on the forum, its very interesting! I decided to experiment with your protocol because I know that I am very deficient in B12 and the active folates. I just wanted to ask your opinion about some of the symptoms I have been getting particularly with the methyl b12. I have generally avoided taking methyl b12 due to bad reactions which I attributed at the time to mercury being stirred up and redistributed. I normally get headaches with it, and it is a very similar reaction to when I take Alpha Lipoic Acid which does seem to chelate mercury in my case....so I assumed this was what was happening with the methy b12. Though I appreciate that there is a lot of debate over whether methyl b12 can have this effect on mercury.
Recently I started on the adenosyl b12 that you recommend, I have never taken that before and it is definitely having a small but positive effect on my mood and energy which is great!
I'm having more trouble with the methyl b12 which I expected. I first took one whole 1000mcg Jarrow methyl b12 tablet a few weeks ago just as an experiment and I felt almost normal psychologically. I have a LOT of neurological/psychological symptoms which vary in their intensity eg terrible memory/cognitive problems, depression, personality changes eg severe rage/irritability, apathy, a lot of the symptoms you have listed in other posts.
Then everything started to go haywire, I had an increase in neurological symptoms and felt like I was literally falling apart mentally and physically, with LOTS of metal taste and increased saliva in my mouth. Anyway luckily when I stopped taking it it passed after a few days!!
Ive started back on the methyl b12 recently, after introducing the adb12, just 1/4 of a tablet but have tried to increase to 1/4 X 3 times a day and starting to feel much the same, a bit like Lisag with a feeling of 'brain damage' and dementia like symptoms, not being able to read or think properly, much worse than regular brain fog, and generally very worrying!
Just to let you know I havent consistently taken hydroxy b12 or cyano b12 over the yrs tho i have taken both from time to time and did have b12 injections many yrs ago...tho dont know what form that was. I do have mercury toxicity and various infections eg lyme & co, & viruses. I guess starting the methylation cycle will inevitably help my body to deal with these burdens and cause symptoms.
I'm taking active folic acid and just stared the jarrow b right too.
I just wondered what your thoughts were and wonder what do you think of the excessive metal taste?
Thanks!
Hi Fraufox,
I have generally avoided taking methyl b12 due to bad reactions which I attributed at the time to mercury being stirred up and redistributed. I normally get headaches with it, and it is a very similar reaction to when I take Alpha Lipoic Acid which does seem to chelate mercury in my case....so I assumed this was what was happening with the methy b12. Though I appreciate that there is a lot of debate over whether methyl b12 can have this effect on mercury.
On another thread here mercury was discussed a bit. I posted a model of what might happen when mercury in the body is exposed to methylb12 considering the moleculer weights of the mb12 molecule compared to the methyl group and the mercury atom and calculated how much Hg could be converted to monomethylmercury by each amount of mb12 at 3 different assumed efficiency rates, 100%, 10% and 1% of mb12, and then what happens. When methylb12 donates a methyl group to mercury as you say, the mercury is stirred up. At that point it can be excreted in the bile by the liver at a known rate of serum half life.
However, as the NORMAL effect of methylb12 on those with many neurological effects of b12 deficiency is to have 52 pickup played with out symptoms. All of the possible "mercury" symptoms are also all possible neurology stirred up without mercury symptoms of methylb12 startup. I honestly don't think there is any way to tell them apart if in fact there were any actually casued by the mercury. Based on the model it isn't possible for you to take enough methylb12 all at once to cause anything like a the lowest level toxic effect from methylmercury becasue of consuming methylb12.
Recently I started on the adenosyl b12 that you recommend, I have never taken that before and it is definitely having a small but positive effect on my mood and energy which is great!
That is good to hear. It doesn't in any way get involved with mercury, only with powering the mitochondria for energy in the body and nervous system.
I have a LOT of neurological/psychological symptoms which vary in their intensity eg terrible memory/cognitive problems, depression, personality changes eg severe rage/irritability, apathy, a lot of the symptoms you have listed in other posts.
Those are primarily methylb12 deficiency symptoms. They can get stirred up when starting mb12 but they do calm down with continued usage. Some of it accurs while healing is happening.
Then everything started to go haywire, I had an increase in neurological symptoms and felt like I was literally falling apart mentally and physically, with LOTS of metal taste and increased saliva in my mouth. Anyway luckily when I stopped taking it it passed after a few days!!
I don't know any way for startup to happen without changes in neurology. Things will change, it is inevitable. As it starts changing the tissues that make the saliva of course that can change too. The metallic taste is common in b12 deficiency. Often people have lost so much of their sense of taste that they can't taste it. As their sense of taste returns, so does a metallic taste for a while. I had that taste on and off for years. Improvment stiops after a few days following the last dose of mb12. These are all normal startup effects.
'brain damage' and dementia like symptoms, not being able to read or think properly, much worse than regular brain fog, and generally very worrying!
These are all b12 deficiency symptoms of various stages of deficiency and healing. They happen much faster while healing and coming back to normal.
I'm taking active folic acid and just stared the jarrow b right too.
By "active folic acid" do you mean Metafolin (methylfolate)? That's what you need to be taking.
I just wondered what your thoughts were and wonder what do you think of the excessive metal taste?
I think that it too will pass. I hope you are taking potassium to prevent problem from rapid healing. I would also suggest selnium which can help with the mercury. Also A,D,E,C calcium. magnesium and Zinc. Got to have those important minerals. Then just keep titrating the methylb12. Until up to 10mg a day sublingual held as long as possible. Things will smooth out and will improve. However, things have been abnormal so long you no longer have your bearings. As things shift around, whch they will do, they all feel abnormal. As one thing after another actually succeeds in healing you will feel successively more and more improved. It can take weeks to months to smooth out a lot. Neurological things take longer to heal than many other things. After things steady out for a bit then comes a time to evaluate. Energy and brainfog need assessment after a few months as there are a lot of factors that affect those things and more adjustments can be made but probably no more need to be made while things are rapidly changing as long as the necessary basics for healing are present. Good luck and feel free to ask questions.
I have lost most of my body hair so not bothered about that.