covid-19

  1. SWAlexander

    Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia

    Abstract Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting “brain fog” and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include EEG slowing...
  2. SWAlexander

    Adult presentation of multisystem inflammatory syndrome (MIS) associated with recent COVID-19 infection: lessons learnt in timely diagnosis and manage

    This includes adults and children. Abstract Multisystem inflammatory syndrome in adults (MIS-A) is an uncommon and under-recognised postinfectious manifestation that presents 4–6 weeks after COVID-19 infection. Patients affected tend to be young or middle-aged, from ethnic minority backgrounds...
  3. SWAlexander

    Clinical features and outcomes of COVID-19 patients with concomitant herpesvirus co-infection or reactivation: A systematic review

    Abstract Background Since the first case of COVID-19 was diagnosed in Wuhan, China in late 2019, concomitant infections with Herpesviridae were documented that were presented from simple skin manifestations to severe life-threatening conditions that may lead to mortality. In this systematic...
  4. SWAlexander

    COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated ind

    I read this paper about a week ago, but I was too angered by the results to post it here at the time. Now, I realize that everyone has the right to know the truth. Abstract Background The Global COVID Vaccine Safety (GCoVS) Project, established in 2021 under the multinational Global Vaccine...
  5. SWAlexander

    A - 104 Basal Ganglia Calcification, Hypothyroidism, and COVID-19: a Case of Possible Fahr’s Syndrome

    Abstract Objective Major neurocognitive Disorder (NCD) is a largely heterogeneous condition with numerous etiological possibilities. Most diagnosed cases have unspecified origins. As such, Fahr’s syndrome (FS) is a rare neurodegenerative condition that clinically presents with varying...
  6. SWAlexander

    Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

    Abstract Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective and subjective components. They are common and debilitating, and can affect the ability to work, yet their biological underpinnings remain unknown. In this prospective cohort study of 1,837...
  7. SWAlexander

    Inflammation and vascular remodeling in COVID-19 hearts

    Abstract A wide range of cardiac symptoms have been observed in COVID-19 patients, often significantly influencing the clinical outcome. While the pathophysiology of pulmonary COVID-19 manifestation has been substantially unraveled, the underlying pathomechanisms of cardiac involvement in...
  8. SWAlexander

    Orthostatic Intolerance after COVID-19 Infection: Is Disturbed Microcirculation of the Vasa Vasorum of Capacitance Vessels the Primary Defect?

    Abstract Following COVID-19 infection, a substantial proportion of patients suffer from persistent symptoms known as Long COVID. Among the main symptoms are fatigue, cognitive dysfunction, muscle weakness and orthostatic intolerance (OI). These symptoms also occur in myalgic...
  9. SWAlexander

    Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19

    My old stomping ground Damaged blood cells". Here we go - finally!!!! Abstract Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can affect multiple organs, among which is the circulatory system. Inflammation and mortality...
  10. SWAlexander

    ‘A silent killer’ - COVID-19 shown to trigger inflammation in the brain

    1 November 2022 Research led by The University of Queensland has found COVID-19 activates the same inflammatory response in the brain as Parkinson’s disease. The discovery identified a potential future risk for neurodegenerative conditions in people who’ve had COVID-19, but also a possible...
  11. SNT Gatchaman

    SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery (2022, Frere et al)

    SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery Justin J. Frere, Randal A. Serafini, Kerri D. Pryce, Marianna Zazhytska, Kohei Oishi, Ilona Golynker, Maryline Panis, Jeffrey Zimering, Shu Horiuchi, Daisy A. Hoagland, Rasmus Møller...
  12. SNT Gatchaman

    Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome, Gaylis et al (2022)

    Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome Norman B Gaylis, Angela Ritter, Scott A Kelly, Nader Z Pourhassan, Meenakshi Tiwary, Jonah B Sacha, Scott G Hansen, Christopher Recknor, Otto O Yang PubMed Link In an...
  13. SeanQHX1

    Strange Symptoms with COVID-19 (and all other infections)

    Hi everyone again! I just recently had COVID-19 just over a week ago and I have to say, I thought it would be much much worse, given my existing health problems too. I only had symptoms for one day, then they basically subsided and I appeared to be asymptomatic. The only symptoms I had though...
  14. SWAlexander

    Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme

    Conclusion Subjects who apparently recovered from mild to moderate SARS-CoV-2 infection show signs of subclinical multi-organ affection related to pulmonary, cardiac, thrombotic, and renal function without signs of structural brain damage, neurocognitive, or quality-of-life impairment...
  15. nerd

    Commentary: COVID-19 variants as moving targets and how to stop them by glycoengineered whole-virus vaccines

    Author: Uri Galili, Department of Medicine, Rush Medical College, Chicago, IL, USA Published: July 25, 2021 PMID: 34304693 doi: 10.1080/21505594.2021.1939924 Preview
  16. SWAlexander

    First COVID-19, Then Myasthenia Gravis: Coincidence or Causal?

    Three patients developed MG after coronavirus infection Myasthenia gravis, an autoimmune neurologic disorder, was associated with COVID-19 in three patients in Italy. Symptoms of myasthenia gravis (MG) appeared 5 to 7 days after fever onset in three patients who had...
  17. nerd

    Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome

    Komaroff AL, Lipkin WI. Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome. Trends Mol Med. 2021 Sep;27(9):895-906 doi: 10.1016/j.molmed.2021.06.002 Epub 2021 Jun 7 PMID: 34175230 PMCID: PMC8180841 Abstract
  18. nerd

    Long COVID and post-infective fatigue syndrome – a review

    Carolina X Sandler, PhD, Vegard B B Wyller, PhD, Rona Moss-Morris, PhD, Dedra Buchwald, PhD, Esther Crawley, PhD, Jeannine Hautvast, PhD, Ben Z Katz, Hans Knoop, PhD, Paul Little, Renee Taylor, PhD, Knut-Arne Wensaas, PhD, Andrew R Lloyd, PhD, Long COVID and post-infective fatigue syndrome – a...
  19. nerd

    Cannabinoid CB2 Receptor Functional Variation (Q63R) is Associated with COVID-19 Severity: from Human Study to Molecular Docking

    This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Mostafa Rastgar, Saeed Samadizadeh, Mohammad Yasaghi et al. Cannabinoid CB2 Receptor Functional Variation (Q63R) is Associated with COVID-19 Severity: from Human Study to Molecular...
  20. Don Quixote

    Long-Covid and neurological problems, Need Help

    Hi all, I have had covid twice. The first time was last year and I did nothing to treat it, so suffered for months with bad chest pain and heart palpitations/tachycardia, blood pressure issues, fatigue and weakness, tinnitus, on and on. I just got covid again almost three weeks ago, but this...
  21. nerd

    Google Trends not showing increased awareness for CFS/ME

    I created this plot to analyze if COVID-19 somehow contributed to an increased awareness for CFS/ME. The latest Google Trends data show increased searches for Long COVID in Google and YouTube - multitudes greater than for CFS/ME. There is no increased awareness for CFS/ME from Long-COVID...
  22. nerd

    Severe COVID-19: A serotonine-mediated disease

    I found this research from Dr. Farid Jalali, and it finally explains why severe COVID-19 is so severe despite antivirals and immune suppressants. It's all driven by serotonin from destroyed platelets. I'm mentioning this because it can also explain the damage to the Blood-Brain Barrier (BBB)...
  23. max_yazhbin

    Gumweed leaf tea helped me overcome Covid

    I have a pre-existing condition, multiple chemical sensitivities, which upon more recent testing looks to be caused by an insufficiency of the appropriate amino acids as well as mercury poisoning which allowed candida, SIBO, H. pylori, and ulcers to flourish. I was worried for a bit when the...
  24. nerd

    What lessons can be learned from Dr. Paul Marik regarding COVID-19?

    The COVID-19 pandemic has really shown me how the medical system works and how politics can influence the progress of a pandemic. I think there are many lessons to learn for CFS/ME. The following are some points from two webinars with Dr. Paul Marik, the leading scientists who pushed...
  25. nerd

    How nutrition can influence Ivermectin's neurological risks and side effects

    Ivermectin (IVM) is an allosteric modulator of GABA-A receptors (GABAaR), glycin receptors (GlyR), and nicotinic acetylcholine receptors (nAChR) (10.1113/JP275236). These receptors don't only play a role in the brain but also in the spinal cord (10.1016/S0165-6147(96)01013-9...
  26. nerd

    What happened to parasite research?

    In face of the current Ivermectin discussion, I'd like to reopen an old post in the context of chronic parasite infection. Firstly, I'd like to cover the nematode Strongyloides Stercoralis. Here is one recent study that shows the prevalence in rural Cambodia and its chronified symptoms...
  27. vision blue

    Poll #2: Compare second vaccine dose to first (and some extra)

    Just setting this up because of the poster who was hoping to get info on reactions to second dose compared to first. Others may have same question. Please check off all that applies. (Note I am hoping that "publicly visible" means only the aggregate is visible. If that is not true, i will edit...
  28. gbells

    My Concerns about the Coronavirus-19 vaccines

    I just had a discussion with my pharmacist about the coronavirus vaccines. I have concerns about the cost to benefit of the vaccines and the possibility of vaccine contamination that might injure patients. It has been discovered that asian countries have a very low covid death rate of around...
  29. Cipher

    Large population study identifies drugs associated with reduced COVID-19 severity

    Large population study identifies drugs associated with reduced COVID-19 severity TLDR: Q10 use was associated with a 81% reduced risk of SARS-CoV-2 hospitalization.
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