I don´t know if this can be a relativ short intervention. It would mean that the lattice (reticularis) has been collapsed. It would be possible to help it by specifically supplement things that are needed there: - 500 mg Tyrosin (->Dopamine) - 250 mg VitC (--> Norepinephren) - 250 mg Tryptophane (-> Serotonin) - 500 mg GABA (it crosses obviously well eneough through the BBB) - ?ng/pg nickel (don´t know if this is necessary -> blocking NMDR, elevating Dopamine) It works almost fabulous (and progredient). Two or three times a day. (Tryptophane can be difficult for the gut and, without tyrsosine, for the brain, in my experiences). If I wouldn´t have taken one single time an antipsychotic I now would be able to work for at least two hours a day. In my case the progredient improvement consists of three interventions: This one Restricting manganese (downregulating iNOS of the microglia). Avoiding sugar, restricting fat a bit (upregulating AChE) There is some hint that ACh contibutes to (high) nitric oxide. ACh is also elevated by nitric oxide. (High nitric oxide would have caused the break down of the inner brain synapse working.) Furthermore it is known (I. Baciu since 1945, and R. Ader 1974) that the nerves via hypothalamus influence the immunesystem. In a rough guess there is nothing not to hope for. Nerves are crucial anyway.