Out of curiosity, has anyone here taken the oils without the cofactors Greg recommends (B2, selenium etc)?
It's not surprising that Greg's recommendations didn't work, since my situation didn't fit Greg's model. After several years of research and experimentation I decided my problem was very likely not CFS/ME, not MTHFR, not Greg's theories. I decided (based on about a dozen clues) that it was mercury poisoning. I started taking the Cutler-recommended "Core Four" (C, E, Mg, Zn) and my massive B12 requirement dropped by half, literally overnight. I proceeded with dental revision and got all my amalgam fillings removed. The last one came out on 12/7/17, and about a week later I took my LAST dose of B12 oil. I haven't needed it for 14+ months now.
Greg never believed me. He has his mental model of how B12 metabolism works (which he understands extremely well) but he refuses to consider there might be other unrelated things that could mess up B12 metabolism. He never accepted that anyone could get mercury-toxic from amalgam fillings, and ridiculed/ignored the studies I presented that didn't agree with his worldview. When I updated him with the good results of the amalgam removals, he responded something like "still flogging the same tired mercury theories I see." He said the Core Four and amalgam removal did "bupkiss" for me, and I got better because 3 years of massive B12 supplementation had suddenly filled up my supplies to the level I needed. (Which he originally told me might take a month.) He didn't explain why 3 years of trying all of his recommendations didn't work, but the problem went away within days of removing the last mercury from my mouth. I gave up on trying to convince him.
If you have the problems Greg's trying to fix, then his recommendations might help you. If you have the problems Freddd is trying to fix, then his recommendations might help you. But if you have something else -- like I did -- then neither one is likely to solve your problem. Figure out your cause so you know what solutions might work for you.
(And good luck with your chelation process, Kathleen!!)