I have been dealing with multiple deficiencies, as well as amalgam issues and my use of the B-12 Oils had increased to about 4 squirts, two of the simple Methyl and two of the Ado/Methyl combo. I've been cleared of amalgam for exactly three months and my current use has dropped to a squirt of each daily (the simple Methyl is less activating if I need something late in the day or at night...) (I find I can 'feel' the oils entering my system very fast, that is, within 15-20 minutes, actually; and I find they seem to last about 6 hours for me, though this may be shifting)
However, I've also been following Fred's protocol (as well as Greg's advice) and came finally--and very significantly--to Boron, which I had titrated up on over the past couple of months. According the Greg, it takes a month or possibly more for cells that haven't been functioning with a particular supplement to die off and new ones to begin to utilize it (or something like this!) and I have found this to be true on multiple occasions. It was only recently when a NutrEval Test showed that I STILL was deficient in B2--and therefore still missing something it needed to get it going and thus wasn't recycling B-12 or Folate--that Greg recommended taking a multi that had some things that many people don't get around to (boron, vanadium, chromium). His recommendation was the Life Extension One per Day that had these things in it. In any case, because it also had alpha-lipoic-acid and folks who still have amalgam in their mouths should stay away from it until they are free and clear, I got what was still missing in a separate supplement, ie the boron, and began to titrate it.
Interestingly, as Fred describes in his REFEEDING thread, I had all the symptoms of refeeding with Boron--ibs, heart irregularities, higher potassium need, excruciating insomnia--and am still, even after two months, refeeding Boron. I have only just reached the 3mg that the NOW tablet contains (and the Life Extension multi) and I will say that Boron has changed my life. My host of symptoms, while still there, respond better, my arthritic, painful hands bend easily for at least portions of the day, I am sleeping more deeply most nights, my need for B-12 had dropped, as has my Folate dose (from about 15mg/day to about 5-6). All in all, it's amazing. And most of all, I have begun on some days to feel 'normal'. Not better, but headed in that direction. This after being ill for about 25 years.
So, I'll have to post this elsewhere, I think, or write a blog. I have been working on methylation issues for the past 3 years--it has been my life, and not happily so, I have to admit. But I have been faithful to it and, as much as I didn't want to be, patient...
That said, this forum lead me down the path that brought me to here and I am beyond grateful. What I have learned is that it's all relevant! Right down to those microminerals. Another shoe could drop, of course. I'm by no means complacent... In fact, I'm working assiduously on my gut now (l-glutamine, probiotics, digestive enzymes, etc).
With a nod of ardent appreciation to
@Athene* and
@Johnmac and
@garyfritz and
@caledonia and
@ahmo and
@stridor and
@Gondwanaland and
@Eastman and many, many others.
Oh, and above all, to
@Freddd and Dr. Gregory Russell-Jones.
