Hip
Senior Member
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@grapes, this might be something of interest:
The over-the-counter drug theophylline greatly potentiates the anti-inflammatory effects of corticosteroids. Ref: 1
So possibly taking theophylline with corticosteroids may allow you to get the same anti-PEM effects at a lower corticosteroid dose. In this study where they added theophylline to the corticosteroid regimen of asthma patients, they used a dose of 250 mg of theophylline daily.
Theophylline also has a vasoconstriction effect, and is thus useful for POTS, to reduce blood pooling in the legs on standing.
The over-the-counter drug theophylline greatly potentiates the anti-inflammatory effects of corticosteroids. Ref: 1
So possibly taking theophylline with corticosteroids may allow you to get the same anti-PEM effects at a lower corticosteroid dose. In this study where they added theophylline to the corticosteroid regimen of asthma patients, they used a dose of 250 mg of theophylline daily.
Theophylline also has a vasoconstriction effect, and is thus useful for POTS, to reduce blood pooling in the legs on standing.