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Dannylingo
Thanks for that. I had an extraordinary 6 month run on B1 with more energy than I have had in years.Unfortunately the positive effect has begun to decline for me. I had the worst day yesterday that I have had in months.
I am taking 1500 mg of B-1. Do you have any suggestions on dosage of the niacin, biotin, b2 and manganese? Are there tests that you can take to check your vitamin balance?
Thanks for your help.
Lynn
I'm not familiar with tests but what I do kno is that thiamine works with basically all the b vitamins work together and vice versa. I find it odd that no were on this forum does people ever consider the Krebs cycle the core of all there ailments.
I personally believe methylation issues is secondary to b1,2,3,5,7 deficiencies. Notice how methyl supplements almost always stimulate you, but don't provide you with atp ? Then you crash.
On the other hand the other b vitamins don't really have a stimulating affect, it's not to say it cant deplete a synergistic vitamin though. For example, if you crash on b1, it coul be anything from niacin to b5 wich work with b1 to form acetyl coa.
If you have too much acetyl coa and not enough oxaloacetate your acetyl coa will go to waste causing less energy. Next what you need to consider is that you is that you might need to pair up b1 with magnesium since they also pair up to activate a different enzyme in an earlier step. If you want to increase oxaloacetate you need to pair up biotin with manganese and nicotinamide.
That will increase ox entering the Krebs cycle to join acetyl coa to produce citric acid wich will give you that energy you need from food. I always wondered why people on this forum never consider studying a little bit of text book biochem to understand what they might be lacking after a vitamin stops working. Usually most of you guys just say "it stopped working" and that the end.