PTSD is the big reason I´m “pushing” to include the endocrinal system in ME/CFS research.
From 1994 to 2016 I led the organization “Adults abused in Childhood worldwide” and almost all displayed symptoms we call today ME/CFS. This was the reason I asked Bill Clinton for research money in 2000 and he made $10 million for Safe Start grants available: http://boxbook.com/letters/letter-from-bill-clinton/
Maybe you like to read: “The Biological Effects of Childhood Trauma” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968319/
The most severe symptoms were expressed by people with sexual abuse:
“Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment”: https://www.nature.com/articles/tp201160
“Childhood adversity increases risk for depression and chronic inflammation”: https://www.sciencedaily.com/releases/2012/07/120703133721.htm
Thanks for the kind reply. I've done a hell of a lot of therapy. I kinda know the roots. Part of what drives the catecholamines is allergy, mcas, whatever because I've really addressed the early life stuff best I can.Oliver3 you asked.
"But if I could stop those PTSD symptoms, surely my body would it improve?"
As you may have read there are many issues involved.
On the Psychological side; are you able to talk or write about your past experience?
Not that it presents the perfect solution, but hiding negative experience drives the whole body. Your Amygdala (our black box) is always reflecting, comparing and warning. That drives up the hormone levels.
On the hormonal part, you may have a catecholamines test done to see what hormones are driving you most.
By reading a lot about abuse and it´s long-term-consequences, you become your own best therapist.
Surely PTSD and parasympathetic activity are intimately correlated. Many Iraq veterans have travelled to South America to use psychedelics to treat PTSD. That in turn stops the sympathetic dominance@Oliver3 Psylocibin is being used to treat depression and PTSD. I'm not sure how that relates to parasympathetic vs sympathetic activation.
Here's a nice article: https://www.nature.com/articles/d41586-021-00187-9