Easy Ozone Transdermal Application Technique
I developed an easy ozone transdermal application technique which I suspect may be just as effective as the ozone full body bags you can buy, but my technique is simpler, quicker, more convenient — and very inexpensive. The total outlay is around £30, which is the cost of an ozone gas generator machine that you can
buy from China on eBay.
Cheap ozone generators like this one can be bought on eBay:
These generators create ozone gas from the oxygen in the air. They pump out ozone gas from a nozzle, and are supplied with a flexible plastic tubing that you attach to the nozzle, as well as some airstones that fix on to the other end of this tubing, so that you can bubble the ozone gas created by the generator into water. The tiny ozone gas bubbles that issue from the airstone are dissolved into the water to make ozonated water. These inexpensive machines typically pump out 400 to 600 mg of ozone per hour.
Easy Ozone Transdermal Application Technique: My Method
You first need to create 60 ml of ozonated water. You do this as follows: place 60 ml (2 fl oz) of tap water into a glass vessel (but don't use plastic containers), and then immerse the airstone of the ozone generator machine into this water, and bubble in the ozone for 30 minutes. This should be done outside (or out of the window), so as not to pollute the indoor air with ozone.
Then immediately splash this 60 ml of ozonated water all over the skin of your naked body, from head to toe, and let it dry into your skin for the next 2 minutes, without putting my clothes on. As the water seeps into your skin, it will bring the ozone dissolved in the water right into your body and bloodstream.
I find that within an hour or two of applying this ozonated water to my skin, my normally congested sinuses and nasal cavity become totally uncongested and nicely opened, and I feel much more relaxed mentally (I find there is a strong anti-anxiety effect of ozone).
I found this ozone therapy also rapidly made my weak leg muscles firmer, with 30 minutes of application (I have slightly weak leg and pelvic girdle muscles). So its conceivable be that this ozone therapy will help ME/CFS patients with muscle symptoms or pain.
I have the impression that this can help kick you out of a bad phase, when your symptoms have got temporarily worse. Ozone seems to produce a beneficial jolt to the system.
This transdermal use of ozone seems much kinder to the body that oral ozone water. If I take ozonated water orally, it really messes up my digestion. I think ozone is a bit rough on the intestinal mucous membranes. Whereas absorbed transdermally on the skin I get no side effects.
General Notes
➤ Much more ozone gas dissolves into cold water than it does into warmer water: twice as much ozone is dissolved into water at 5°C, compared to water at 20°C (ref:
here). So for best results use tap water than has been cooled down in the fridge (or just put an ice cube in the water)
➤ Ozonated water will lose most the ozone dissolved in it within an hour, so you have to make this ozonated water fresh every time you apply it to your body (the half life of ozone in water at room temperature is 20 minutes, ref:
here).
➤ Do not use a plastic vessel to make your ozonated water, because ozone can react with the plastic and contaminate the water. A glass vessel should be used.
➤ Ozone is more stable if the water is acidic, so it is a good idea to place say a tablespoon of vinegar in your 60 ml of water.
When water is acidic (at pH less than 6) the dissolved ozone remains in its molecular O
3 form. But when the water is more alkaline (at pH 7 or higher), this molecular O
3 ozone rapidly decomposes into the hydroxyl radical. Even in neutral water at pH 7, about 50% of the ozone dissolved into the water decomposes into the hydroxyl radical. Ref:
here.
Mechanism of Action of Ozone Therapy
There is scant research into the therapeutic mechanisms of ozone. However, a very interesting scientific analysis of ozone therapy can be found in chapter 4 of the book 'OZONE. A New Medical Drug' by Velio Bocci. Bocci suggests that the benefits of ozone therapy arise from the reactive oxygen species (ROS) and the lipid oxidation products (LOP) created by ozone application.
In effect, ozone therapy provides benefits by creating short-term, acute oxidative stress in the body.
Because ozone causes acute oxidative stress, although this may have therapeutic benefits, it may be a good idea not to perform ozone therapy too often (say no more than twice a week), to avoid depleting the body of antioxidants.
I will just quote the conclusion of chapter 4 of this book here:
What Happens When Human Blood is Exposed to a Therapeutic Dose of Oxygen-Ozone?
"Both gases dissolve in the water of plasma depending upon their solubility, partial pressure and temperature. While oxygen readily equilibrates between the gas and the blood phases, the ten-fold more soluble ozone cannot equilibrate because it reacts with biomolecules (PUFA, antioxidants) present in the plasma. The reaction yields hydrogen peroxide (among other possible ROS) and lipid oxidation products (LOPs).
The sudden rise in plasma of the concentration of hydrogen peroxide generates a gradient, which causes its rapid transfer into blood cells where, in a few seconds, it activates several biochemical processes and simultaneously undergoes reduction to water by the efficient intracellular antioxidant system (GSH, catalase, GSH-Px).
This critical step corresponds to a controlled, acute and transient oxidative stress necessary for biological activation, without concomitant toxicity, provided that the ozone dose is compatible with the blood antioxidant capacity.
While ROS are responsible for immediate biological effects (Figure 1), LOPs are important as late effectors, when the blood, ozonated ex vivo, returns into the circulation upon reinfusion (Figures 2 and 3).
LOPs can reach any organ, particularly the bone marrow where, after binding to receptors in submicromolar concentrations, elicit the adaptation to the repeated acute oxidative stress, which is the hallmark of ozonated autohemotherapy. Upon prolonged therapy, LOPs activity will culminate in the
upregulation of antioxidant enzymes, appearance of
oxidative stress proteins (haeme-oxygenase I as a typical marker) and
probable release of stem cells, which represent crucial factors explaining some of the extraordinary effects of ozonetherapy (Chapter 8).
It must be emphasized that blood exposed to ozone undergoes a transitory oxidative stress necessary to activate biological functions without detrimental effects. The stress must be adequate (not subliminal) to activate physiological mechanisms, but not excessive to overwhelm the intracellular antioxidant system and cause damage. Thus, an excessive ozone dose or incompetence in manipulating this gas can be deleterious. On the other hand, very low ozone doses (below the threshold), are fully neutralised by the wealth of plasma antioxidants and can produce only a placebo effect.
The concept that ozonetherapy is endowed with an acute oxidative stress bothers the opponents of this approach because they consider it as a damage inflicted to the patients, possibly already under a chronic oxidative stress. they do not believe that ozonetherapy induces a multivaried therapeutic response already well documented in some diseases.
Moreover they do not distinguish the chronic oxidative stress (cos) due to an endogenous and uncontrolled hyperoxidation with the small and transient oxidative stresses that we can precisely perform ex vivo with the ozone dose."
Source: chapter 4 of the book
OZONE. A New Medical Drug, by Velio Bocci, Springer 2005.
This paper also succinctly describes the method of action of ozone:
The airways are precluded in this therapy, which uses ozone-enriched autologous blood transfusion; therefore, lung toxicity resulting from oxidative stress is avoided. Ozone, per se, does not enter the organism;
the effects that are observed are mediated by the rapid oxidation of certain substances in the blood in the transfusion recipient.
In appropriate concentrations, this can up-regulate the synthesis of antioxidants in blood (7). This property has been very actively investigated with respect to the protection against free radical damage associated with heart (8), kidney (9) and liver (10) disorders.