OAT - Organic Acid Testing - is it useful?

[pspa123]

It makes sense to me to start with the basic lab test which I think is PLP according to Mayo, Labcorp, etc. Thanks all for your insight.

 

[pspa123]

So.... on the basic blood test, my result is 35.7 ug/L with the lab range (Labcorp) being 5.3-46.7. What do I know, but that sure doesn't sound to me like a profound deficiency from "pyroluria" requiring supplementation at 300 mg./day (3 times the official upper limit of safety), as I have been advised?

 

[pamojja]

What do I know, but that sure doesn't sound to me like a profound deficiency from "pyroluria" requiring supplementation at 300 mg./day

As already said, with regular B6 blood test you're only sure if it shows deficiency. With normal or above nothing for sure.

 

[sue1234]

So, I know this is an old thread, but bringing it back up because I was re-reading my old 2018 OATS test results. I had elevated malic, fumaric, and citric acid results. Their interpretation says if all of these three are elevated, it could point to a Cytochrome C Oxidase deficiency, which affects the mitochondrial function. Does anyone here have any similar pattern or knowledge of this?

I also have elevated 3-hydroxy-glutaric and 3-methylglutaric levels. The first says it could be related to a genetic glutaric aciduria disease, and the second could be either genetic or mitochondrial. Any insight would be welcomed!