Sorry,i wrote your name wrong Wanja. The kindling model on the nervous system role in chronic illness,ME ,drug withdrawal,mold toxicity etc has been discussed here and all over the net many times if your interested,but still it is a theory just like anything else .
Kindling Theory
According to the kindling theory, repeated exposure to an initially subthreshold stimulus can eventually exceed threshold limits, resulting in persistent hypersensitivity to the stimulus and ultimately, spontaneous behavioral manifestations. Kindling among patients with ME/CFS might appear after prolonged stimulation of the limbic-hypothalamic-pituitary axis, either by high-intensity stimulation.....etc etc