https://selfhacked.com/2016/03/12/top-15-scientific-health-benefits-of-resveratrol-with-references/Interesting. I take resveratrol. It makes me feel better but I'll be paying attention as to why.
#2 point says that resveratrol increases glutamate intake by astrocytes, which then use it to make glutamine, which is then used as an energy source and also it is then used to synthesize BOTH gaba and glutamate in neurons.
Glutamine synthase is very similar to GAD67 in that it balances glutamate and GABA.
I just realized GAD67 uses PLP as a cofactor, I guess that is another reason why high b6 is extremely important for excitatory/inhibatory balance. It is speculation of mine that resveratrol can reach deep into cells and prevent oxidation of b6.
B6 seems to be very important in excitatory/inhibatory balance, through enabling taurine synthesis and enabling gaba synthesis through GAD67.
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