Hi all, I am 3 weeks in.. still weaker, worse neurological symptoms. However, sleep seems improved and may be too early to tell but I think less headaches.
Was reading this study in relation to the gender differences in metabolism of glucose and fat. I am quite cognitively impaired, so I can’t read it in great detail but pulled out a few relevant quotes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161229/
On pg 11: “there were also indications of reduced mitochondrial fatty acid oxidation only in female ME/CFS patients (
32). Adding to PDH inhibition, reduced mitochondrial fatty acid oxidation would expectedly compromise the supply of acetyl-CoA further and thereby increase the dependency of category II amino acids for alternative fueling of the TCA cycle, as shown in our study.”
On page 13: “...all categories of ME/CFS women, including obese women, had lower mean levels of the ketogenic amino acids than healthy control women...”
I’m not so good w science stuff, but wondering if this diet just might not work for many female patients. I suppose it is possible tho that the diet could reverse some of these findings, and cause more amino acids to be created. Thoughts?
Also, I just had some tests done and have low Lactate dehydrogenase (LDH). Which is an enzyme used to convert glucose to energy. So maybe I am just screwed either way, glucose or fat!
Still sticking with it..