My labs showed that I was in the trap after being prescribed 5-HTP for sleep. Tryptophan was high and 5 HIAA was so high that my doctor suspected a carcinoid tumor which I didn't have. These stayed elevated for about 2 years.
In the meantime, my doctor had me start h-bot which I ended up doing two to three times a week for about two years, mainly to increase oxygen in my blood, and to try to go after my chronic infections.
How about the time Phair was sharing his IDO2 metabolic trap theory, my doctor and I noticed that my 5 HIAA and tryptophan trending downward. They continued to trend downward into the normal range while I continued on h-bot.
So, it seemed that I stumbled into the right answer, before they announced that oxygen could be the answer.
Due to COVID, I discontinued h-bot in late February, and my 5 HIAA bounced up above the normal range again.
I owe you a bit more of an answer, @Sushi but studies have shown h-bot to reduce oxidative stress, which is useful.
Would be interesting if Holy Basil helped this, or oxymatrine as it would at least give us a guide to if my research and trials have yielded anything interesting with regards to IDO. Holy Basil gives us zero side effects, but I as I said I use 5-10g organic powder rather than cheap extract tablets. The powder is still very cheap. 3 sweeteners or ribose powder is a must though!!