for example live blood taken from a vein is simply re-injected under the skin in sheep autovaccination and was proven effective in the studies discussed earlier in this thread. That would also have had v low counts of bacteria in it - or the animal would have been dead already from acute bacteraemia.
also, since the patients with CFS/ME are already exposed to antigens at some level from the biofilm colonies inside them ( if Markov is correct ) - adding more antigens - no matter if its a small amount more - is unlikely to cause immunotolerance as it will be moving in the other direction.
Re oral tolerance:
Oral tolerance is described as a physiological phenomenon that contributes to prevent pathological conditions to food protein and commensal microbiota, inhibiting responses that could cause damage such as hypersensitivity reactions, lymphocyte proliferation, and antibody formation . Most of all, tolerance induced to these natural antigens that reach the intestinal lumen seems to be an analog of tolerance to self-components. Since microbiota and dietary antigens are part of our physiological interface with the external environment, tolerogenic mechanisms in the mucosal surfaces must have evolved to treat these antigens as complementary or quasi-self.