If cortisol doesn’t, or can’t, apparently treat the problem of chronically low endogenous cortisol, what will?
Yes, from my understanding of the literature and testimonials is that low-dose cortisol replacement for ME is just a temporary bandaid that works for a while but then eventually stops working, causes a number of long-term side effects, and turns into this monster your have to wean off of.
The body normally makes about 40 mg. of cortisol per day, so as long as a person supplements with less than that on a daily basis, the adrenal glands won't shut down their own production to zero. So many of the side effects from cortisol supplementation of 40 mg. or more can for the most part be avoided.
That said, even low-dose supplementation can be a problem for some people. Fortunately, it wasn't for me. It took me from about 4% functionality to around 25%, which is about where I've been at the the past many years. I have little to no concern about my continued use of low-dose cortisol supplementation.