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Cardiopulmonary responses to exercise in an individual with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome during long-term treatment with intravenous saline: A case study
Article type: Research Article
Authors: Davenport, Todd E.*; a; b | Ward, Michael K.a | Stevens, Staci R.b | Stevens, Jaredb | Snell, Christopher R.b | VanNess, J. Markb; c
Affiliations: [a] Department of Physical Therapy, School of Health Sciences, University of the Pacific, Stockton, CA, USA | Workwell Foundation, Ripon, CA, USA | [c] Department of Health, Exercise, and Sport Science, College of Pacific, University of the Pacific, Stockton, CA, USA
Abstract:
BACKGROUND:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) causes significant impairment in daily activities, including the ability to pursue daily activities. Chronotropic intolerance is becoming better characterized in ME/CFS and may be the target of supportive treatment.
OBJECTIVE:To document the effect of repeated intravenous (IV) saline administration on cardiovascular functioning and symptoms in a 38-year old female with ME/CFS.
METHODS:The patient received 1 L of 0.9% IV saline through a central line for a total of 675 days. Single CPETs were completed periodically to assess the effect of treatment on cardiopulmonary function at peak exertion and ventilatory anaerobic threshold (VAT). An open-ended symptom questionnaire was used to assess subjective responses to CPET and self-reported recovery time.
RESULTS:Improvements were noted in volume of oxygen consumed (VO2), heart rate (HR), and systolic blood pressure (SBP) at peak and VAT. Self-reported recovery time from CPET reduced from 5 days to 1–2 days by the end of treatment. The patient reported improved quality of life related, improved capacity for activities of daily living, and reduced symptoms.
CONCLUSIONS:IV saline may promote beneficial effects for cardiopulmonary function and symptoms in people with ME/CFS, which should be the focus of formal study.
Keywords: Treatment, exercise testing
DOI: 10.3233/WOR-203214
Journal: Work, vol. Pre-press, no. Pre-press, pp. 1-7, 2020
Received 13 September 2019
|
Accepted 29 March 2020
|
Published: 27 June 2020
Article type: Research Article
Authors: Davenport, Todd E.*; a; b | Ward, Michael K.a | Stevens, Staci R.b | Stevens, Jaredb | Snell, Christopher R.b | VanNess, J. Markb; c
Affiliations: [a] Department of Physical Therapy, School of Health Sciences, University of the Pacific, Stockton, CA, USA | Workwell Foundation, Ripon, CA, USA | [c] Department of Health, Exercise, and Sport Science, College of Pacific, University of the Pacific, Stockton, CA, USA
Abstract:
BACKGROUND:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) causes significant impairment in daily activities, including the ability to pursue daily activities. Chronotropic intolerance is becoming better characterized in ME/CFS and may be the target of supportive treatment.
OBJECTIVE:To document the effect of repeated intravenous (IV) saline administration on cardiovascular functioning and symptoms in a 38-year old female with ME/CFS.
METHODS:The patient received 1 L of 0.9% IV saline through a central line for a total of 675 days. Single CPETs were completed periodically to assess the effect of treatment on cardiopulmonary function at peak exertion and ventilatory anaerobic threshold (VAT). An open-ended symptom questionnaire was used to assess subjective responses to CPET and self-reported recovery time.
RESULTS:Improvements were noted in volume of oxygen consumed (VO2), heart rate (HR), and systolic blood pressure (SBP) at peak and VAT. Self-reported recovery time from CPET reduced from 5 days to 1–2 days by the end of treatment. The patient reported improved quality of life related, improved capacity for activities of daily living, and reduced symptoms.
CONCLUSIONS:IV saline may promote beneficial effects for cardiopulmonary function and symptoms in people with ME/CFS, which should be the focus of formal study.
Keywords: Treatment, exercise testing
DOI: 10.3233/WOR-203214
Journal: Work, vol. Pre-press, no. Pre-press, pp. 1-7, 2020
Received 13 September 2019
|
Accepted 29 March 2020
|
Published: 27 June 2020