I am now trialing Dr. Lynch's
B-minus - a B12 and folate free B-complex with bioactive forms like R5P and P5P. It has a bit of niacin to counteract overmethylation. Currently on day 3 at 1/2 capsule. Got a significant energy boost, so far it's good!
I'm trialing it, too -- if you count taking it once, LOL! It says to take it after breakfast, and I found out why, by taking it in the evening. (Heck it was the only way I could separate it from other supps to see the effect!) I am quite wary of B2, because it made my low-back inflammation return in December (which went away when I stopped it).
Here's what happened: Wide awake from 4-6:00 am. Tight neck & back muscles. I finally took potassium at 6:00 am and went back to sleep. Got up around 8:00 to eat, but right back to bed around 8:30. The whole day was like that: get up, go back to bed and sleep some more.
When I try it again, it will be in the morning, and just 1/2 capsule or less!
In December I was trialing FMN (flavin mononucleotide), and this B-minus contains R5P sodium. Are those very different?