Because a doctor prescribed if to help my sleep and triggered the IDO2 trap, which took 18 months of hyperbaric oxygen to get rid of.Why do you think is 5-HTP not advisable?
I don't have any theories. I listen to what my doctors say dnf then read research studies and info on the web. There are a number of reasons that SAMe is not advisable. My doctors have always avoided SAMe got myself and others, and used precursors.I'm quite sure it is SAMe that get's depleted and not its precursors. How can SAMe be more counterproductive than its precursors? Feel free to share your theory in the separate post that I opened about the methylation cycle
They have worked well for me, with glutathione. I seemed to always be short of isoleucine and leucine.I'd be interested in how you understand that they can reverse PEM? What's their mechanism of action?
This describes what they do:
No big secret here. There is a slide which lists 5 troublesome SNPs in the YouTube videos from Phair's presentation at the Stanford Symposium. Probably in his paper too.