metabolic trap

  1. junkcrap50

    Amsterdam scientists find an enzyme (IDO2) that could be the culprit of #LongCovid: Prolonged IDO2 activity & associated cellular stress in PASC.

    They found the IDO2 enzyme in "insane amounts" in Long Covid patients in all kinds of cells causing "a kind of collective suicide" as well as impaired mitochondrial function and Krebs Cycle dysfunction. They say it's clear that IDO2 continues to rage after the virus is defeated and IDO1...
  2. Joel98

    Can I try 5-HTP despite the possible Metabolic Trap without irreversibly worsening it?!

    Hello, I'm wondering if I can test 5-HTP capsules without worsening the possible Metabolic Trap. If I understand it correctly, it is still unclear whether you have too much or too little serotonin as a result. My symptoms tend to feel like too little and a urine test (which I know has little...
  3. Jwarrior77

    The Causes of ME/CFS, POTS, and Chronic Illness - A patients opinion

    This is my opinion on the causes of these illnesses coming from a patient who suffers from these conditions. My opinion is based on my own experience, research from the top scientists studying this, and also other patients such as Jeff Wood, Jen Brea, and others who have contributed a lot of...
    • Jwarrior77
    • Thread
    • connective tissue eds lyme disease mcas metabolic trap microbiome neuroinflammation toxic mold vagus nerve viral persistence
    • Replies: 7
    • Forum: General ME/CFS Discussion
  4. nerd

    Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

    Vancassel S, Capuron L and Castanon N (2018) Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms. Front. Neurosci. 12:499. doi: 10.3389/fnins.2018.00499 Abstract How is this relevant? One of the unsolved questions of...