Abilify- Stanford Clinic Patients

[Martin aka paused||M.E.]

2mg pramipexole... no change

 

[Martin aka paused||M.E.]

I’m thinking of reintroducing Abilify right know. It’s a month now.

 

[jaybee00]

I think the Fawcett article says you need 2-3 weeks at 2 mg.

 

[SueJohnPat]

For me it pretty much stopped working. Side effects were bad sleep.

I am having success with the drug but my sleep has been screwed up more that usual. Just soldiering through at this point.

 

[hmnr asg]

I am having success with the drug but my sleep has been screwed up more that usual. Just soldiering through at this point.

What is your dose? And how long have you been in it?

 

[jaybee00]

I’m hearing Stanford recommends super low doses like 0.25 mg three times per week (maybe someone mentioned this earlier in this thread).

 

[leokitten]

I’m hearing Stanford recommends super low doses like 0.25 mg three times per week (maybe someone mentioned this earlier in this thread).

Of pramipexole or aripiprazole?

 

[jaybee00]

For Abilify (aripiprazole).

 

[Martin aka paused||M.E.]

I’m hearing Stanford recommends super low doses like 0.25 mg three times per week (maybe someone mentioned this earlier in this thread).

Whuuut?

 

[hmnr asg]

I’m hearing Stanford recommends super low doses like 0.25 mg three times per week (maybe someone mentioned this earlier in this thread).

how do you even measure that much ?
I have an appointment in three months so i will get back to everyone about this. In the meantime, if anyone else is in touch with their clinic, can you confirm that this is the case? this sounds hard to believe!

 

[leokitten]

how do you even measure that much ?
I have an appointment in three months so i will get back to everyone about this. In the meantime, if anyone else is in touch with their clinic, can you confirm that this is the case? this sounds hard to believe!

Aripiprazole oral solution 1 mg/ml
https://m.goodrx.com/aripiprazole?d...rride=aripiprazole&quantity=1&sort_type=price

 

[Jessie 107]

I’m hearing Stanford recommends super low doses like 0.25 mg three times per week (maybe someone mentioned this earlier in this thread).

How come Whitney is on 2mg then??

 

[Martin aka paused||M.E.]

Very severe again... can’t speak and hardly use my phone... maybe Abilify has left my body...

 

[Martin aka paused||M.E.]

I think the Fawcett article says you need 2-3 weeks at 2 mg.

The problem is that if this worsening continues I need a tube in 2 weeks again

 

[SueJohnPat]

What is your dose? And how long have you been in it?

I take 0.25 mg in the morning been on it for approximately 2months.

 

[jaybee00]

I think the purpose of every other day dosing is to allow the receptors to reset—I don’t know this might be BS.

Maybe a Bonilla patient could send an email to him to confirm the dosing.

 

[hmnr asg]

I think the purpose of every other day dosing is to allow the receptors to reset—I don’t know this might be BS.

Maybe a Bonilla patient could send an email to him to confirm the dosing.

The half life of abilify is 75 hours, so even if you take it every other day you will reach a constant plasma level. I think ? @leokitten can you confirm ?

 

[leokitten]

The half life of abilify is 75 hours, so even if you take it every other day you will reach a constant plasma level. I think ? @leokitten can you confirm ?

You will still eventually reach steady state as long as you’re dosing on a consistent basis. It will normally take 4-5 half lives to achieve steady state. Explanation https://www.nuventra.com/resources/blog/what-is-steady-state-concentration/

 

[Martin aka paused||M.E.]

You will still eventually reach steady state as long as you’re dosing on a consistent basis. It will normally take 4-5 half lives to achieve steady state. Explanation https://www.nuventra.com/resources/blog/what-is-steady-state-concentration/

What could be the benefit? Less side effects? Long live?

 

[leokitten]

I think the purpose of every other day dosing is to allow the receptors to reset—I don’t know this might be BS.

Maybe a Bonilla patient could send an email to him to confirm the dosing.

No this won’t be the case. For most drugs and constant dosing regimens you will reach a steady state plasma (and brain) concentration after 4-5 half lives. The difference for example between 0.25 mg/day and 0.25 mg/every other day will results in a somewhat lower steady stare concentration in your body between the two.