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@Wolfcub - it might be better to try increasing the Bs one at a time, starting low and going slow, and seeing how you react to each one. You may need more of one and not another - e.g., I have felt much better since taking methylfolate in addition to B12, as well as extra B6 (P-5-P) (which was shown to be severely deficient by Nutreval testing) and B1 - thiamine, in the form of benfotiamine. However, I felt worse when I tried extra B2, though many people need more B2. We're all different.
However, you should be on the lookout for low potassium when increasing B12 and methylfolate. These vitamins may make you feel better initially for a day or 2 but it's not uncommon to suddenly feel much worse with severe fatigue and other symptoms of low potassium. This thread explains why.
Another possibility is to develop symptoms of low phosphorous which I don't think is as common, but I've had this too. It started after I increased my B1 - initially I had a nice boost in energy and then the next day severe fatigue. It felt different than low potassium, and also potassium didn't help with this fatigue. I'd done reading about refeeding syndrome (see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440847/ ) and theorized that perhaps my phosphorous had tanked. So I drank I think 3 glasses of kefir (high in phosphorous) and sure enough by the afternoon the horrible fatigue was going away. I still get symptoms of low phosphorous off and on - the chief symptom for me is severe fatigue but I also noticed it makes my brain fuzzy. So many ways we can get fatigued with this illness!
was your B1 too high? You may not need more. I've been told that benfotiamine is more bioavailable than regular thiamine. I don't have diabetes, but benfotiamine is the form that is supposed to help with diabetic neuropathy.
So if your B1 was too high, then I'm guessing benfotiamine might make it even higher - or maybe I misunderstood you?
Sorry to hear that! Have you ever tried andrographis? It's an amazing herb which has helped me a lot. I used to get a lot sicker a lot more often until I started taking it. It's an immunomodulator, so I take a break from it every once in awhile. And if I get acutely sick (like you are), I'll add in an echinacea/goldenseal combo to the andrographis and this has all been very effective for me.have had a horrible viral infection, still chairbound.
so riddle me that????
Afraid I am not the right person to answer this! I don't know if high B1 on blood work is like high B12 on blood work, in that high B12 blood work does not necessarily mean you have too much B12 but rather can be an indication that you are having trouble getting it into the cells and utilizing it. Though I think B12 is harder to absorb and metabolize than the other B's. Anyways, yes Freddd very well may know more about this. And I know there are people on this board who know a lot more about the B's in general than I do --Why is it a baddie to have too high B1.