Like many people with ME/CFS, I have sleep issues. Part of these issues seem to be related to both high night time cortisol and low daytime cortisol. I have read about a number of things that might help this, but what I cannot find is what specifically causes this pattern. The closest I have come are some vague comments about how stress causes us to excrete lots of cortisol. While I agree this is part of the issue, I don't see it explaining why cortisol would be higher at night time...if anything, I imagine stress-induced cortisol output should be higher during the day, or at least day and evening cortisol would be equal. Does anyone have some insight?