I don't know. For me, the amount I needed would have been very hard sublingual. But, most of the time I took mine in footbaths. I'd been doing bicarb FBs for awhile, then added the K (K+) as well as aminos. this worked well for me, easier than drinking so much.
I have a number of files listing which herbs affect which genes and then one only had to research the drug used to find out how it clears to determine if there will be that sort of problem. Other problems are things like if the herb thins the blood, prevents clotting, causes bleeding (COX-2 inhibitors), increases or decreases absorption. There are many ways supplements can interact with drugs.