aquariusgirl
Senior Member
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just read that Prof Nancy Klimas is asking patients to share their 23andme results with her for some research project....so maybe you could share your work with her...???\
just read that Prof Nancy Klimas is asking patients to share their 23andme results with her for some research project....so maybe you could share your work with her...???\
I think that is thyroid related.skin texture/ wrinkling ( onset one year ago )
when I introduced selenium there was as if another layer of fog was removed. And today after taking my first choline/inositol dose I felt tired for a while but within a few hours I noticed a boost in mental function/mood. My skin looks better and less gray/yellow/pale in fact it somehow looks like Ive been tanning lol which I havent done in forever due to sun intolerance. Sleep has been uninterrupted for the last four nights for the first time in years.
1. Seeing your dosages, you are taking an awful lot of Choline. This means that your TMAO levels will skyrocket which is not good in the long run. I seriously advise you to cut back on Choline.
2. You might be stopping TUDCA too early. Of course i do understand that TUDCA is expensive. Nevertheless what i suggest is that you eliminate alcohol completely for a couple of months and re-evaluate. Remember that Liver functioning can be a major player for your recovery.
Dehydroepiandrosterone (DHEA), the major precursor of androgens and estrogens, has several beneficial effects on the immune system, on memory function, and in modulating the effects of diabetes, obesity, and chemical carcinogenesis. Treatment of rats with DHEA influences expression of cytochrome P450 (P450) genes, including peroxisome proliferator-activated receptor α (PPARα)- and pregnane X receptor (PXR)-mediated induction of CYP4As and CYP3A23, and suppression of CYP2C11. DHEA treatment elevated the expression and activities of CYP3A4, CYP2C9, CYP2C19, and CYP2B6 in primary cultures of human hepatocytes. Induction of CYP3A4 in human hepatocytes was consistent with studies in rats, but induction of CYP2Cs was unexpected.
Perhaps the worst is CYP7B1 :