Trouble balancing Niacin and Thiamin

[Tigersmom]

Since increasing Niacin a week ago, I have had terrible balance of vitamins and bad symptoms. I tried returning to my original dosing the but issues didn’t resolve. I can’t seem to balance the levels of: B3, B1, (I think Magnesium, but could be other minerals)

Attached is a chart of my attempts at balancing and the effects I’ve felt.

Some thoughts:
Increasing B3 somehow seemed to make irrelevant the very hard balancing act between Methyl vitamins (mainly methyl B12) and vitamins that seemed to slow methylation (B3/B6). Suddenly how much Methyl B12 I did or didn’t take didn’t really matter.
Increasing B3 also seemed to decrease the need for Molybdenum

My best guess: B3 is somehow effecting a mineral (?) that is also effected by B1 but in the opposite way. Ie B3 increases a mineral that B1 decreases, or vice versa. Because of the Uric Acid issues and a lessened need for Molybdenum I am thinking:
B3 increases absorption of Molybdenum, which decreases Copper; B1 dumps copper.
But I haven’t found any support for this in research and I’m eating full servings of Pumpkin Seeds and Sunflower Seeds which are both high in copper everyday.

 

[LINE]

I am pretty sure that B3 will upregulate methylation (it always made me bonky). B2 is always helpful for me as is B6 and Pantothenic Acid (B5).

Everybody responds differently which I keep in mind.

 

[sb4]

I experimented with Niacin for my poor carb tolerance issues. It seemed to help that a little however after 2 or 3 days I started feeling off in the afternoon and quite depressed. I stopped then restarted the niacin a while later and the same thing happened.

 

[LINE]

[QUOTE
Increasing B3 also seemed to decrease the need for Molybdenum

My best guess: B3 is somehow effecting a mineral (?) that is also effected by B1 but in the opposite way. Ie B3 increases a mineral that B1 decreases, or vice versa. Because of the Uric Acid issues and a lessened need for Molybdenum I am thinking:
B3 increases absorption of Molybdenum, which decreases Copper; B1 dumps copper.
But I haven’t found any support for this in research and I’m eating full servings of Pumpkin Seeds and Sunflower Seeds which are both high in copper everyday. [/QUOTE]

Copper levels could be low and yes, you are correct in that there is a relationship between copper/uric acid and molybdenum. Copper also happens to be a necessary nutrient for immune function, I think it is involved in neutrophil production and is involved in metabolic processes in the cell (Cytochrome C etc) and many other functions in the body. 1989-v04n02-p099.pdf (traceelements.com)

Best test is through Trace Elements Inc. who can test mineral levels. This is a trusted company (I have used them for 30 years). Correct mineral balance is overlooked but very important. I do not think that guessing is productive.

 

[Tigersmom]

You're right. I'm getting my minerals tested by hair i'll report back. It was copper in this instance that made me feel better, but you are right I don't want to guess.

 

[LINE]

You're right. I'm getting my minerals tested by hair i'll report back. It was copper in this instance that made me feel better, but you are right I don't want to guess.

Yes, please let me know - I have many hours of study in minerals.