Selective translocator protein (TSPO) agonists

EddieB

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After the dramatic reduction of symptoms yesterday from the Ativan, has me thinking that possibly some type of neuro Med could be helpful, even short term. However, there seems to paradox with most, that they have the potential side effect of weakening the esophagus sphincter. And also for some, the fear of dependency.

So far, the only ones that seem safer are LDN and buspirone. I’m not entirely certain on the LDN, but buspirone is listed as strengthening to esophagus. More study needed.
 

ljimbo423

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After the dramatic reduction of symptoms yesterday from the Ativan, has me thinking that possibly some type of neuro Med could be helpful, even short term.
It sure seems like it. Even if you need to take Ativan, maybe you can take it say 2-3 days a week to avoid dependence. Then find something like LDN or buspirone to take on the days in between.

You might need to think outside the box to get a handle on this.:)
 

EddieB

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It sure becomes a chicken/ egg thing, as to what is causing what. I’m certain my gut bacteria/ balance is screwed up, but if the gut is consistently under neurological stress, well that’s not going to make for a healthy environment. I’m not under much external stress, but my guts are in a near constant state of tension. And I have at times struggled with anxiety/ panic attacks over my entire life. In looking back, the amitriptlyne I was on for a few years may have been providing some stability, but the fatigue/ out of breath side effects were awful. As you know, I’ve tested for everything possible, and tried all the natural methods, with no help. Proceeding with caution...thanks!
 
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ljimbo423

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It sure becomes a chicken/ egg thing, as to what is causing what. I’m certain my gut bacteria/ balance is screwed up, but if the gut is consistently under neurological stress, well that’s not going to make for a healthy environment. I’m not under much external stress, but my guts are in a near constant state of tension. And I have at times struggled with anxiety/ panic attacks my entire life.
It could have very easily been me saying these very same things!! Good luck going forward!