, one question it would interesting to ask Dr Chia is: What is the relative efficacy of oxymatrine versus matrine?
Is one better than the other for immunomodulation and fighting enteroviruses?
In Sophora root, there is both oxymatrine and matrine, and since Equilibrant contains Sophora root extract, I guess it will also contain both oxymatrine and matrine. In any case, I understand that oxymatrine converted to matrine in the body when taken orally.
What I have found is that the pharmaceutically pure oxymatrine product from Alternative Medicine Solutions
(containing 300 mg oxymatrine per capsule) does not make me dizzy, whereas the White Tiger oxymatrine (with 200 mg oxymatrine per tablet) does cause dizziness.
I think this is because White Tiger is a herbal extract made from 1 gram of Sophora extract per tablet, so will contain oxymatrine, matrine, and other compounds from Sophora, and one of these compounds, probably matrine, must induce dizziness.
So if oxymatrine is just as good (or better) than matrine for immunomodulation purposes, the pure oxymatrine product from Alternative Medicine Solutions may be the one to go for, especially because it also does not make you dizzy.
Also, a related question is: Does oxymatrine potentially work for all forms of ME/CFS
(whether triggered by enterovirus, herpes family viruses, or even triggered by vaccination), or is oxymatrine only useful enterovirus-associated ME/CFS?
By the way, do you remember my wild speculation in this
earlier post about how the high 30% success rate (for major improvements) Dr Chia gets with oxymatrine might be connected to the fact Dr Chia is based in Southern California, and assuming many of his patients are locals, they are going have higher sunshine exposure, which leads to higher levels of vitamin D, which effects Th1/Th2 in complex ways.
Well, in this recent thread
(which I think you have already seen), @gregh286
reported that a combo of oxymatrine
and high dose vitamin D
(25,000 IU) put him into full remission (only for 3 weeks so far though). But when he had previously tried oxymatrine on its own, it did not work at all. So perhaps vitamin D does boost the efficacy of oxymatrine.